DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS1 and SPBC1683.12

DIOPT Version :9

Sequence 1:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_595068.1	Gene:	SPBC1683.12 / 2539910	PomBaseID:	SPBC1683.12	Length:	482	Species:	Schizosaccharomyces pombe

Alignment Length:	517	Identity:	104/517 - (20%)
Similarity:	190/517 - (36%)	Gaps:	142/517 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLFLSIVVNYMAKFNAG-VAVVAMTNAENTNPNFPEYDWNEMERSYILSSFFWGYILTQFMGGWL 83
            |.|||    ::.:.|.| .|||.:  .|:......:|       |..:|.|:..||..:.....|
pombe    51 LYFLS----FLDRANIGNAAVVGL--KEDLKLQAYQY-------SAAVSVFYATYITAETPSVLL 102

  Fly    84 CRRYGARITMFVSTIGSALLVVLIPWCVSWGGWQAYCAIRMSMGLFQGFLFPCIHAHLANWCPVK 148
            .:::|....:....||.:|:.:..  |.....| :....|:.:|:.:|..|||:..:::.....:
pombe   103 VKKFGPHYYLSAMIIGWSLVTIFT--CFVRHYW-SLVLTRLLLGICEGGFFPCLSLYISMTYKRE 164

  Fly   149 ER-NRLGALANTGIDCGTLVAMFASGLL-AASSIGWP--GIFYVSCG----VGVLW---CIVWWI 202
            |: .||..|.......|....:.|:||. ...|.|.|  |..|:..|    :..||   |:
pombe   165 EQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGLPNWGWLYIIEGLISAISALWILFCL---- 225

  Fly   203 FGANQPRESKFIG--EAELNYIETSINSSRKAEEAELKATGPIPVPW---KAIWTSVPFWALMVT 262
              .:.|..::|:.  |.||..|        :||:.: |..|.....|   :..:.....:...|.
pombe   226 --PDDPSTARFLNPREKELMKI--------RAEQRQ-KYMGSPNFDWTQFRKAFKDPKMYMSCVI 279

  Fly   263 RCCQS---WGYSTLQTEMPAYMNGVLLMDMKSNAL---YSALP-YLTSWVMAFVYLIIADILLTR 320
            :.||.   :|.||       ::..:|.:::..::|   |.::| |....:..:|..:::|....|
pombe   280 QFCQDLVLYGIST-------FLPSILKLELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIR 337

  Fly   321 G--------------IMSITGIRKSVNSIAFFVPAAAL-----IGVSFLDNTQK---TLAVVLMC 363
            |              |:.:.....:.|.:|.::.|..|     :.:::::|...   ..|..|.|
pombe   338 GWFIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNITWINNNMAPHYRRATALGC 402

  Fly   364 ANVGINAGSTIGSTINTIDLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFI 428
                   ..|||          |.||::.|.|..:|       |..:|      |.       |.
pombe   403 -------NQTIG----------NLAGVIAGQVYRSS-------PYKLG------HG-------FA 430

  Fly   429 ISAVIFCVGNIVYVAFGKMVNQPWDAPDFMDKQRSSNLQEVGHSKALEAQGSEKVEEAKRNE 490
            :...:  ||.:...|....:            ||.:.:::       |....|:|:|.|..:
pombe   431 LGCTV--VGTLTATAMRFYL------------QRQNKIKQ-------EILNGERVDEKKERD 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS	18..444	CDD:119392	96/469 (20%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	97/481 (20%)
SPBC1683.12	NP_595068.1	MFS	47..417	CDD:119392	88/420 (21%)
SPBC1683.12	NP_595068.1	2A0114	50..417	CDD:273326	88/420 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050