Protein Alignment MFS1 and slc-17.6

DIOPT Version :10

• Sequence 1: NP_726254.1
• Gene: MFS1 / 246519
• FlyBaseID: FBgn0050272
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_490947.2
• Gene: slc-17.6 / 171781
• WormBaseID: WBGene00017398
• Length: 546
• Species: Caenorhabditis elegans
• Alignment Length: 508
• Identity: 124/508 - (24%)
• Similarity: 223/508 - (43%)
• Gaps: 59/508 - (11%)

  Fly    17 QTFLLF-LSIVVNYMAKFNAGVAVVAMTNAEN--TNPNFPEYDWNEMERSYILSSFFWGYILTQF 78
            ||.||. .:.||..:.:...|:|:|.:..:.|  .:|:. ..:|:..|::.|.:||:.|..:..|
 Worm    28 QTALLISAACVVFGLMRTCFGMAMVDIVRSGNGTFHPDL-HMEWSGDEQANIHTSFYIGAFIAVF 91

  Fly    79 MGGWLCRRYGAR----ITMFVSTIGSALLVVLIPWCVSWGGWQAY---CAIRMSMGLFQGFLFPC 136
            ...:|.::.|.:    ..:.::..||    :|.|:...:  .::|   .|||:.||...||:.|.
 Worm    92 PSEFLAKKLGPKNLLSFALLLNIFGS----LLTPFSAIY--LRSYFPVAAIRLIMGFGYGFVIPA 150

  Fly   137 IHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSI--GWPGIFYVSCGVGVLWCIV 199
            ....:::|.|:.|::...|:..||...|..|:||.:..|.....  |||.:|.|...:|.::.::
 Worm   151 GSVLISSWFPLSEKSTAMAIFTTGNQIGIAVSMFLTAKLCQLHFFEGWPLVFIVYGLIGAVFLVI 215

  Fly   200 WWIFGANQPRESKFIGEAELNYIETSINSSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTRC 264
            |.:..|::|||||:|...||.||:.......:||               .|..:.|:..:::..|
 Worm   216 WHVRLADKPRESKYITATELTYIKGGKQRRNRAE---------------TIVRATPYMKIILNGC 265

  Fly   265 ---------CQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTR 320
                     .||:....|.|.:|.|......|::..|.::|:||:....:...::.||||.:..|
 Worm   266 VCAICACSFAQSFVLVALVTYLPKYNQIAFKMNLTHNGIWSSLPFFIQMITKLLFAIIADKVKQR 330

  Fly   321 GIMSITGIRKSVNSIAFFVPAAALIGVSF--LDNTQKTLAVVLMCANVGINAGSTIGSTINT--I 381
            .: :.|.:.|..|:||.|..|..::..::  .|:.:    :|.:...|.:.|.|......||  :
 Worm   331 KV-NATAVTKVSNAIASFASAIFIVIAAYGPFDSAE----LVQLSIIVSMAAFSAYVPGYNTSIV 390

  Fly   382 DLSPNHAGILMGIVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGK 446
            .::|.....:.......:.|...|.|:::|.|.......| |:..|...|.:..|..:::..||.
 Worm   391 TVAPQFTAFISSYAQLYAQIASTLAPIVIGRITSHGTIYE-WKCAFYSLAGVLAVTGLIFQIFGH 454

  Fly   447 MVNQPW-DAPDFMDKQR---SSNLQEVGHSK--ALEAQGSEKVEEAKRNESEG 493
            ...:|| :.|......|   |..:.|.|..|  .||....|...|:|.:...|
 Worm   455 GRTEPWGETPSNATSARLSTSVTMCEDGMCKLTLLEKHNHEFRTESKISSGSG 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS1	NP_726254.1	MFS_SLC17	18..445	CDD:340876	107/451 (24%)
slc-17.6	NP_490947.2	MFS	30..453	CDD:475125	106/450 (24%)