DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG30203 and CG30046

DIOPT Version :10

Sequence 1:NP_725128.2 Gene:CG30203 / 246514 FlyBaseID:FBgn0050203 Length:924 Species:Drosophila melanogaster
Sequence 2:NP_725129.1 Gene:CG30046 / 36334 FlyBaseID:FBgn0050046 Length:839 Species:Drosophila melanogaster


Alignment Length:892 Identity:354/892 - (39%)
Similarity:487/892 - (54%) Gaps:118/892 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 IVLLILLSSEVRG-----VCNRIPQGASGPRSPVDDNFKILIDGNPETYVPEHQYNVSLSCPINM 64
            :|.|:||.|.|.|     :|.|.|.....|:||||:||.|.:.||||||:...:|||||:.....
  Fly     9 LVELLLLGSLVIGRVSSLICTRRPANTGSPKSPVDENFMISVSGNPETYILGQEYNVSLNAFNGH 73

  Fly    65 KFVSFTLVVEAEDPSAAFGGQDMTGHFELLGVGDTRFSTSCENMVENTNTNAKIYIAVSWIAPRN 129
            :::||.:.:|.|  :..|...|..|.|||..:.:||||.:|.|||||||||:|.::.::|:||..
  Fly    74 RYISFIMALENE--NGDFSYNDDLGRFELSDLIETRFSPNCINMVENTNTNSKTHMHLTWVAPSE 136

  Fly   130 PDSGCVLIKAGVVQHRDVWFLDDGFLTKRICPEEIDELNSL-TPPLET---CCACDEAKYEIVLE 190
            |.||||||:|.|.|||:||.:|||.||||||.|..|::.|. |.|...   |||||||:||::.|
  Fly   137 PGSGCVLIRATVQQHREVWHMDDGGLTKRICEEVTDDVESQPTAPAAVDVPCCACDEARYELIFE 201

  Fly   191 RKWARNTHWKDFPSEDWRTRLGEVIGASHSHSYRYWAYGGRASKGMKELAEHGATRTLENEIREN 255
            ..|:||.|.||||:..|.||..|::||:||..||:|..|..||..|||.|||.::|.||.|...|
  Fly   202 GVWSRNLHPKDFPTRGWETRFCELLGAAHSSDYRFWESGELASVAMKEYAEHCSSRLLEREFSIN 266

  Fly   256 TQNGEVRTIIKAPGIPYRPKTFGTTLANARLDPVHHQISLAAKIDPSPDWILGVAGLELCLSNCT 320
            .::.::||||||.| |..|.....|:|:.|:||:||.:|.|:||:||||||:||.||||||.|||
  Fly   267 FRDQKIRTIIKARG-PSYPNISSKTMASVRVDPIHHMVSFASKIEPSPDWIVGVTGLELCLRNCT 330

  Fly   321 WLERKVLNLYPWDIGTDSGPSYMSSDEPQVPPDVVRRITSSYPSDHRSPFYDDTGAPMKPLATLY 385
            |:|.||:||||||:||||||:|.|||:|||||||:||:.|.:|:|.||||||.:|.||||:|.|.
  Fly   331 WMEEKVINLYPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSDFPNDPRSPFYDISGTPMKPMAILT 395

  Fly   386 LTRKKLYIRECEEVPQEG----PLECAVHPWNEWTNCSTRCGQGYSHRQRSFKNPNLAANFNCDR 446
            :.|:::|.|.|.:.....    |.||..|||:.|::||::||.|..:|:|.:|.|.||..:||:.
  Fly   396 VKRQRIYERRCADEDSNNDPDVPRECFTHPWSSWSDCSSKCGVGMQYRRRVYKQPELARVYNCNE 460

  Fly   447 RLEEFRQCQGTQCG-----AAEEELEGEEPG---LGMENPPSSGSMAECQLTNWGEWSPCTKTCG 503
            ...|.|:|||..||     ...||.|..||.   :|.:  ||....|||:|::||.||||:.|||
  Fly   461 AQYEERECQGEMCGQNNLMREPEEFEDLEPDPRRIGYQ--PSQQRRAECELSSWGSWSPCSVTCG 523

  Fly   504 RGSSTRTRDYYNPQARQRCLSVMRIPLEETRECIGSDCGGTIPDN--------------GELDG- 553
            .|...|.|.|.||||...|..|.|:.|:|||:|.|.||.|::|.:              |.:.| 
  Fly   524 DGYEMRQRQYLNPQAEFDCQGVHRMELQETRKCSGRDCLGSLPGSYSTDMDSPYGGASPGRIGGN 588

  Fly   554 ------FPEPDVFGETD--HGGYMGKTTSWNSKQEHSSLGS-GNQAWNRKPYNSWKDKSLSNP-- 607
                  .||.:.||:.|  ..|.:|.....|.|      |: ||.|.||:. |..:|.....|  
  Fly   589 MYGPQLEPEAENFGDYDDSRNGAVGGFEVGNLK------GNIGNWALNRQT-NLGRDVPSLRPTN 646

  Fly   608 ----RDNAQESPNLPFDQIENPQRPAYNPSDNMGGYDKGFPPTNSYSN----DKLVGNRPGYNDF 664
                |..|::|....:.....|..|.....:....:.:  .|:|.|.:    .::|..|..:...
  Fly   647 YDRARQQAEKSERTTWSGQSRPDDPRLEDVERAPWHRQ--RPSNKYGSIVEAPEMVSPREPWQRA 709

  Fly   665 NSDYNNKDAYNDYTTPSFTSRTPFGSRYPNQQETVEGNTNDINGNYNVVQDYCFEKPYASTLPCF 729
            | ::.|.|.|           ||.|...|:.             :|.     ||:....:...|.
  Fly   710 N-NFGNPDMY-----------TPGGDVDPSL-------------SYR-----CFQMVQTAQPRCH 744

  Fly   730 AKPVVESNYWFYDHEDHECKIFTTDNCDQNRNRFRTLTACEGTCLQPQINMERSENDAMDLYGRR 794
            .: .:..::|||:....||.::..|.||:|.|:||....|| .|.||               |..
  Fly   745 DQ-TITGHFWFYNFCADECMLYAADQCDRNVNKFRRWEDCE-KCRQP---------------GMA 792

  Fly   795 SYDQKQTRGRPYDQTSGIAYGQTEGRSYDQKVGKSYDRTFGRSYKQT 841
            :..|:.|.....:....|  .|.|.|:.::|...:..|.:|.|..:|
  Fly   793 ALQQEHTNSPQCEDFRAI--WQAEQRAREEKRPSNRRRNYGDSRYRT 837

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG30203NP_725128.2 Reeler 18..160 CDD:260081 71/141 (50%)
Spond_N 183..380 CDD:461924 115/196 (59%)
TSP1_spondin 407..459 CDD:480609 23/51 (45%)
TSP1_spondin 487..541 CDD:465948 28/53 (53%)
PTZ00441 <492..>713 CDD:240420 69/254 (27%)
KU <739..773 CDD:197529 14/33 (42%)
CG30046NP_725129.1 Reeler 28..167 CDD:260081 71/140 (51%)
Spond_N 194..390 CDD:461924 115/196 (59%)
TSP1 425..473 CDD:214559 21/47 (45%)
TSP1_spondin 507..561 CDD:465948 28/53 (53%)

Return to query results.
Submit another query.