DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30203 and spon2a

DIOPT Version :9

Sequence 1:	NP_725128.2	Gene:	CG30203 / 246514	FlyBaseID:	FBgn0050203	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_571082.1	Gene:	spon2a / 30201	ZFINID:	ZDB-GENE-990415-160	Length:	334	Species:	Danio rerio

Alignment Length:	298	Identity:	91/298 - (30%)
Similarity:	135/298 - (45%)	Gaps:	20/298 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   177 CCACDEAKYEIVLERKWARNTHWKDFPSEDWRTRLGEVIGASHSHSYRYWAYGGRASKGMKELAE 241
            |.|...|.|.:|....|:..|..|.:|......:..:::..:|:..||.|..|..||.|||..||
Zfish    38 CSARGPASYIVVFTGHWSPQTFPKQYPLFRPPAQWSKLMVVTHNEQYRLWQEGAPASDGMKSFAE 102

  Fly   242 HGATRTLENEIRENTQNGEVRTIIKAPGIPYRPKTFGTTLANARLDPVHHQISLAAKIDPSPDWI 306
            .|.|..|..:.:|..:...|.::.:..||   |...|.:.....|.|....:||..|:.|||||.
Zfish   103 QGLTVDLVKDAKEARKRRSVGSMYRTAGI---PSGIGHSSTEVLLTPRSPLVSLIVKLIPSPDWF 164

  Fly   307 LGVAGLELCLSNCTWLERKVLNLYPWDIGTDSGPSYMSSDEPQVPPDVVRRITSSYPSDHRSPFY 371
            :||.||.|| ....|.:....:|:|:|.|||||.::.|.:.|..||:.:..|||..|:...:.||
Zfish   165 VGVDGLNLC-EGGKWKQEVTFDLHPFDAGTDSGFTFSSPNFPTTPPENITMITSQKPNHPANSFY 228

  Fly   372 DDTGAPMKPLATLYLTRK-KLYIRECEEVP-------------QEGPLECAVHPWNEWTNCSTRC 422
            ......:.||||:::.|: :|.:|:...:.             .|.||:|.|..|:.|..|...|
Zfish   229 YPRLNELPPLATIWVKRQSRLPVRQQNRLSNHILPDASKPHRFSETPLDCEVSMWSSWGLCFGPC 293

  Fly   423 GQ-GYSHRQRSFKNPNLAANFNCDRRLEEFRQCQGTQC 459
            .: |..||.|........:...|. .|||..:|....|
Zfish   294 ARGGLRHRTRYILLKPANSGSPCP-ELEEQEECTPHNC 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30203	NP_725128.2	Reeler	18..160	CDD:260081
		Spond_N	183..372	CDD:283999	62/188 (33%)
		TSP1	411..459	CDD:214559	13/48 (27%)
		TSP1	492..541	CDD:214559
		KU	<739..773	CDD:197529
spon2a	NP_571082.1	Spond_N	44..230	CDD:283999	63/189 (33%)
spon2a	NP_571082.1	TSP1	283..330	CDD:214559	13/47 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D240419at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820