DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30203 and Spon2

DIOPT Version :9

Sequence 1:	NP_725128.2	Gene:	CG30203 / 246514	FlyBaseID:	FBgn0050203	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_598664.3	Gene:	Spon2 / 100689	MGIID:	1923724	Length:	330	Species:	Mus musculus

Alignment Length:	325	Identity:	101/325 - (31%)
Similarity:	140/325 - (43%)	Gaps:	48/325 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 NSLTPPL---ETCCACDEAKYEIVLERKWARNTHWKDFPSEDWRTRLGEVIGASHSHSYRYWAYG 229
            ::.:.||   ..|.|...|:|.|....||::....|.:|......:...::||:||..|..|...
Mouse    22 STTSQPLGGESVCTARPLARYSITFIGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKN 86

  Fly   230 GRASKGMKELAEHGATRTLENEIR---ENTQNGEVRTIIKAPGIPYRPKTFGTTLANARLDPVHH 291
            ...|.|:::.||.|....|..||.   |..|:  |..:..||.|   |...|.|.....:.|.|.
Mouse    87 EYVSNGLRDFAERGEAWALMKEIEAAGEKLQS--VHAVFSAPAI---PSGTGQTSTELEVHPRHS 146

  Fly   292 QISLAAKIDPSPDWILGVAGLELCLSNCTWLERKVLNLYPWDIGTDSGPSYMSSDEPQVPPDVVR 356
            .:|...:|.|||||.:|:..|:|| ....|.|:.||:|||.|.|||||.::.|.:...:|.|.|.
Mouse   147 LVSFVVRIVPSPDWFVGIDSLDLC-EGGRWKEQVVLDLYPHDAGTDSGFTFSSPNFATIPQDTVT 210

  Fly   357 RITSSYPSDHRSPFYDDTGAPMKPLA-----------------TLYLTRKKLYIRECEEVPQEGP 404
            .||:|.||...:.||......:.|:|                 :|.|..:...|.:...|| |.|
Mouse   211 EITASSPSHPANSFYYPRLKSLPPIAKVTFVRLQQSPRAFAPPSLDLASRGNEIVDSLSVP-ETP 274

  Fly   405 LECAVHPWNEWTNCSTRCGQ-GYSHRQRSFK-NPNLAANFNCDRRLEEFRQCQGTQCGAAEEELE 467
            |:|.|..|:.|..|...||: |...|.|..: .|   ||             .||.|...|||.|
Mouse   275 LDCEVSLWSSWGLCGGPCGKLGAKSRTRYVRVQP---AN-------------NGTPCPELEEEAE 323

Fly 468 467
Mouse 324 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30203	NP_725128.2	Reeler	18..160	CDD:260081
		Spond_N	183..372	CDD:283999	66/191 (35%)
		TSP1	411..459	CDD:214559	13/49 (27%)
		TSP1	492..541	CDD:214559
		KU	<739..773	CDD:197529
Spon2	NP_598664.3	Spond_N	40..227	CDD:368927	67/192 (35%)
Spon2	NP_598664.3	TSP1	279..329	CDD:214559	19/61 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3539
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810