DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG18853 and CRY2

Sequence 1:NP_724615.1 Gene:CG18853 FlyBaseID:FBgn0042173 Length:330 Species:Drosophila melanogaster
Sequence 2:NP_066940.3 Gene:CRY2 HGNCID:2385 Length:593 Species:Homo sapiens

Alignment Length:343 Identity:65/344 (19%)
Similarity:104/344 (30%) Gaps:119/344 (35%)


  Fly    38 ITRLLQDFRCEGCANNNKSAKDKVAGEKQEHQHQQQTQDQQTGQGQSNYTNGGHCLGE------- 95
            :|||..::..|.......:|..|:|.|                .|....|...|.|.:       
Human   112 VTRLTFEYDSEPFGKERDAAIMKMAKE----------------AGVEVVTENSHTLYDLDRIIEL 160

  Fly    96 -------DYAHFRPIGVIRTAFPEKRAVPRQSIVGSRL---RGIIQLNDGVFTNPEHSLEGLEDF 150
                   .|..|:.| :.|...|:|   |...:...::   |..||.|.    :..:.:..||:.
Human   161 NGQKPPLTYKRFQAI-ISRMELPKK---PVGLVTSQQMESCRAEIQENH----DETYGVPSLEEL 217

  Fly   151 SH--------LW----------LIYHFHR-----NNSHPKAKADNFCFYNEHYDSLKGLSSWA-- 190
            ..        :|          |..|..|     |...|:..|      |....|..|||.:.  
Human   218 GFPTEGLGPAVWQGGETEALARLDKHLERKAWVANYERPRMNA------NSLLASPTGLSPYLRF 276

  Fly   191 ---------YQTLDAHRKDKRDPCYSLEELEKSLTYDDLWNSAQLQLVREGKMHGFLRMYWAKKI 246
                     |:..|.::|.||:....| .|...|.:.:.:.:|.....|..:|.|       ..|
Human   277 GCLSCRLFYYRLWDLYKKVKRNSTPPL-SLFGQLLWREFFYTAATNNPRFDRMEG-------NPI 333

  Fly   247 ---LEWTATPEHALEYAILLNDKYSLDGRDPNGYVGCMW---------SIGGVHDMGWKERAIF- 298
               :.|...||...::|              .|..|..|         ..|.:|.:.....|.| 
Human   334 CIQIPWDRNPEALAKWA--------------EGKTGFPWIDAIMTQLRQEGWIHHLARHAVACFL 384

  Fly   299 --GKVRYMNYQGCRRKFD 314
              |.: :::::...|.||
Human   385 TRGDL-WVSWESGVRVFD 401

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG18853NP_724615.1 UPF0066 100..>163 CDD:294485 17/89 (19%)
CRY2NP_066940.3 PhrB 22..510 CDD:223492 65/344 (19%)
FAD_binding_7 307..505 CDD:308829 21/118 (18%)
Required for inhibition of CLOCK-ARNTL-mediated transcription. {ECO:0000250} 390..489 3/13 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG0415
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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