DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30087 and CG42694

DIOPT Version :9

Sequence 1:	NP_725489.2	Gene:	CG30087 / 246446	FlyBaseID:	FBgn0050087	Length:	277	Species:	Drosophila melanogaster
Sequence 2:	NP_001188994.1	Gene:	CG42694 / 10178792	FlyBaseID:	FBgn0261584	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	289	Identity:	74/289 - (25%)
Similarity:	122/289 - (42%)	Gaps:	55/289 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKTSPAWFVIAICLIRQQRIVDAQFLNPLCGVTYESQTAMRVVNGKEAVIRSAPFMVYVTNNSLT 65
            |:|..||.::...|   |..|:::||:..||....:|:..::...:      |.::.:::|.:..
  Fly     1 MQTLFAWLLMLTVL---QSHVNSKFLDDYCGAPISNQSITKLRQPQ------AGWLAHISNGTHV 56

  Fly    66 HCGGSILNSRYILTAAHC--VFPNLRLRLGEHNIRTDPDCQGSNCSPRSEEYGIMKAITHRFYNA 128
            .|.||:::.:::|:||.|  |...|.::||..|....|                      .:|..
  Fly    57 LCSGSLISKQFVLSAAQCIDVHGKLFVQLGVSNATKSP----------------------HWYTV 99

  Fly   129 ANHV----------NDIALLKLNRSINFNVHIQPICILLNPASAPSVATYQTF---GWGETKKNG 180
            :|.|          .||.||||::|:::|..:.||||.||..:...|...|.|   .|....||.
  Fly   100 SNVVIPSHSGKRLQRDIGLLKLSQSVDYNDFVYPICIALNTNTLDMVKILQNFTTSAWLSKNKNP 164

  Fly   181 FPHLLQTAELRAYDAAYCSRSFHAYMNGNQICAGHEER-DTCAGDSGGPLVTR-VDFDGVKRYLQ 243
                 ||..|.......|..:....:...:|||...:| ::|..|||..|... :....:.|.:.
  Fly   165 -----QTIVLSQLSRDRCKLNLSGNVTPKEICAASLQRNNSCFIDSGSALTQPIIQGSNIVREML 224

  Fly   244 LGIVSY--GPTDCQSPGVYTYVPNYINWI 270
            .||..|  |.:.|..|.:|..|...:.||
  Fly   225 FGIRGYVNGRSWCSEPAIYIDVAECVGWI 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30087	NP_725489.2	Tryp_SPc	41..270	CDD:214473	60/247 (24%)
CG30087	NP_725489.2	Tryp_SPc	42..272	CDD:238113	62/248 (25%)
CG42694	NP_001188994.1	Tryp_SPc	46..256	CDD:304450	61/235 (26%)
		Tryp_SPc	46..253	CDD:214473	59/233 (25%)
		Tryp_SPc	319..505	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I4848
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000404
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108863
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.890