Protein Alignment ATP6V1C2 and Atp6v1c2

DIOPT Version :8

• Sequence 1: XP_011508641.1
• Gene: ATP6V1C2 / 245973
• HGNCID: 18264
• Length: 437
• Species: Homo sapiens
• Sequence 2: NP_001153104.1
• Gene: Atp6v1c2 / 68775
• MGIID: 1916025
• Length: 437
• Species: Mus musculus
• Alignment Length: 437
• Identity: 401/438 (92%)
• Similarity: 416/438 (95%)
• Gaps: 0/438 (0%)

Human     1 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAE 65
            |||||||||||||||||||||||.||||||||:||||||||||||||||||||||||||||||||
Mouse     1 MSEFWLISAPGDKENLQALERMNNVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAE 65

Human    66 SLIRRMAQSVVEVMEDSKGKVQEHLLANGGLKGKMKCLKIDLTSFVTHFEWDMAKYPVKQPLVSV 130
            |||:||||||||||||||||..|.||||||||.||||||||||||||||||||||||.|||||||
Mouse    66 SLIKRMAQSVVEVMEDSKGKAHETLLANGGLKEKMKCLKIDLTSFVTHFEWDMAKYPAKQPLVSV 130

Human   131 VDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLL 195
            |||:||||||||.|||||||||:.||.|||||||:|.||||||||||||||||||||||||:|||
Mouse   131 VDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKRSTGNLFTRTLSDIVSKEDFVLDSEYLITLL 195

Human   196 VIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREF 260
            |||||.:::|||||||||||||||||||||.||.||||||||||||||||||.|||||||.||||
Mouse   196 VIVPKSSFAQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREF 260

Human   261 YYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLGNPDRPAAGQTDRERE 325
            |||||||:||||||.||||||||||.||||||||||:|:.||||||.|||||.|||||||||:||
Mouse   261 YYDEKEIKREREEMTRLLSDKKQQYPTSCVALKKGSATYRDHKVKVAPLGNPARPAAGQTDRDRE 325

Human   326 SEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREV 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
Mouse   326 SEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREV 390

Human   391 LNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD 437
            |||||||||||||.||||||||||||||:||||||||||||||||||
Mouse   391 LNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1C2	XP_011508641.1	V-ATPase_C	5..427	CDD:308707	386/422 (91%)
		3-helical coiled coil	55..75	CDD:270211	19/20 (95%)
		3-helical coiled coil	130..156	CDD:270211	22/26 (85%)
		3-helical coiled coil	284..361	CDD:270211	70/77 (91%)
Atp6v1c2	NP_001153104.1	V-ATPase_C	5..427	CDD:281248	386/422 (91%)
		3-helical coiled coil	55..75	CDD:270211	19/20 (95%)
		3-helical coiled coil	130..156	CDD:270211	22/26 (85%)
		3-helical coiled coil	284..361	CDD:270211	70/77 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C33930683
eggNOG	1	0.900				E1_COG5127
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H15866
Inparanoid	1	1.050	775	1.000	Inparanoid score	I8096
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0001431
OrthoInspector	1	1.000				T2444629
orthoMCL	1	0.900				OOG5_150069
Panther	1	1.100			LDO	PTHR10137
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R1630
TreeFam	1	0.960
	14	14.290