Protein Alignment ATP6V1C2 and Atp6v1c2

DIOPT Version :8

• Sequence 1: XP_011508641.1
• Gene: ATP6V1C2 / 245973
• HGNCID: 18264
• Length: 437
• Species: Homo sapiens
• Sequence 2: NP_001014221.1
• Gene: Atp6v1c2 / 362802
• RGDID: 1359430
• Length: 425
• Species: Rattus norvegicus
• Alignment Length: 437
• Identity: 393/438 (90%)
• Similarity: 407/438 (93%)
• Gaps: 12/438 (3%)

Human     1 MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAE 65
            |||||||||||||||||||||||:||||||||:||||||||||||||||||||||||||||||||
  Rat     1 MSEFWLISAPGDKENLQALERMNSVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAE 65

Human    66 SLIRRMAQSVVEVMEDSKGKVQEHLLANGGLKGKMKCLKIDLTSFVTHFEWDMAKYPVKQPLVSV 130
            |||:|||||||||||||||||.|:|||||          :|||||||||||||||||.|||||||
  Rat    66 SLIKRMAQSVVEVMEDSKGKVHENLLANG----------VDLTSFVTHFEWDMAKYPAKQPLVSV 120

Human   131 VDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLL 195
            |||:||||||||.|||||||||:.||.|||||||||.||||||||||||||||||||||||:|||
  Rat   121 VDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKKSTGNLFTRTLSDIVSKEDFVLDSEYLITLL 185

Human   196 VIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREF 260
            |||||.:|.|||||||||||||||||||||.||.||||||||||||||||||.|||||||.||||
  Rat   186 VIVPKSSYVQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREF 250

Human   261 YYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLGNPDRPAAGQTDRERE 325
            |||||||:||||||.|||||||||||||||||||||:|:.||||||||||||.||.|||.|  ||
  Rat   251 YYDEKEIKREREEMTRLLSDKKQQYQTSCVALKKGSATYRDHKVKVTPLGNPTRPTAGQND--RE 313

Human   326 SEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREV 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||
  Rat   314 SEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREV 378

Human   391 LNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD 437
            |||||||||||||.||||||||||||||:||||||||||||||||||
  Rat   379 LNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1C2	XP_011508641.1	V-ATPase_C	5..427	CDD:308707	378/422 (90%)
		3-helical coiled coil	55..75	CDD:270211	19/20 (95%)
		3-helical coiled coil	130..156	CDD:270211	22/26 (85%)
		3-helical coiled coil	284..361	CDD:270211	69/77 (90%)
Atp6v1c2	NP_001014221.1	V-ATPase_C	5..415	CDD:281248	378/422 (90%)
		3-helical coiled coil	55..75	CDD:270211	19/20 (95%)
		3-helical coiled coil	120..146	CDD:270211	22/26 (85%)
		3-helical coiled coil	274..349	CDD:270211	69/77 (90%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C33923349
eggNOG	1	0.900				E1_COG5127
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H15866
Inparanoid	1	1.050	774	1.000	Inparanoid score	I7584
OMA	1	1.010
OrthoDB	1	1.010				D1016088at2759
OrthoFinder	1	1.000				FOG0001431
OrthoInspector	1	1.000				T2461061
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			LDO	PTHR10137
Phylome	1	0.910		0.800	Consistency score
TreeFam	0	0.000	Not matched by this tool.
	12	12.410