Protein Alignment FXN and fxn

DIOPT Version :10

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_001076485.2
• Gene: fxn / 556389
• ZFINID: ZDB-GENE-070209-286
• Length: 200
• Species: Danio rerio
• Alignment Length: 183
• Identity: 93/183 - (50%)
• Similarity: 115/183 - (62%)
• Gaps: 30/183 - (16%)

Human    29 RPAELAPLCGRRGLRTDIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLG-----HPG 88
            |....|.:|||.       ..|           .::|.|  |:.::|     |..||     |..
Zfish    43 RSVSSANICGRH-------TQC-----------FDRILN--KRDLHL-----SAPLGEEKAHHLR 82

Human    89 SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQ 153
            .:.|..||||||||||:||::||||.|:.:|..||||.|.:||||||:|.|.|||||||||||:|
Zfish    83 EISEAEYERLAEETLDALADYFEDLTDENFTGLDYDVVFSNGVLTVKVGSDHGTYVINKQTPNRQ 147

Human   154 IWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYS 206
            ||||||:||||||||||:.|||:||.|.||.||:.||:...||.:|||.|.:|
Zfish   148 IWLSSPTSGPKRYDWTGERWVYTHDAVPLHSLLSKELSIIFKTNIDLSHLIHS 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	71/97 (73%)
fxn	NP_001076485.2	mito_frataxin	88..185	CDD:132463	70/96 (73%)