Protein Alignment FXN and fxn

DIOPT Version :8

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_001076485.1
• Gene: fxn / 556389
• ZFINID: ZDB-GENE-070209-286
• Length: 169
• Species: Danio rerio
• Alignment Length: 183
• Identity: 94/184 (51%)
• Similarity: 116/184 (63%)
• Gaps: 30/184 (16%)

Human    29 RPAELAPLCGRRGLRTDIDATCTPRRASSNQRGLNQIWNVKKQSVYLMNLRKSGTLG-----HPG 88
            |....|.:|||.       ..|           .::|.|  |:.::|     ||.||     |..
Zfish    12 RSVSSANICGRH-------TQC-----------FDRILN--KRDLHL-----SGPLGEEKAHHLR 51

Human    89 SLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKLGGDLGTYVINKQTPNKQ 153
            .:.|..||||||||||:||::||||.|:.:|..||||.|.:||||||:|.|.|||||||||||:|
Zfish    52 EISEAEYERLAEETLDALADYFEDLTDENFTGLDYDVVFSNGVLTVKVGSDHGTYVINKQTPNRQ 116

Human   154 IWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALKTKLDLSSLAYS 206
            ||||||:||||||||||:.|||:||.|.||.||:.||:...||.:|||.|.:|
Zfish   117 IWLSSPTSGPKRYDWTGERWVYTHDAVPLHSLLSKELSIIFKTNIDLSHLIHS 169

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	71/98 (72%)
fxn	NP_001076485.1	Frataxin_Cyay	54..161	CDD:279789	74/107 (69%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C246048371
eggNOG	1	0.900				E1_COG1965
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H47908
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010				D1372185at2759
OrthoFinder	1	1.000				FOG0004540
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_128372
Panther	1	1.100			LDO	PTHR16821
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
ZFIN	1	1.500
	9	9.300