Protein Alignment FXN and Fxn

DIOPT Version :10

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_001382061.1
• Gene: Fxn / 499335
• RGDID: 1565754
• Length: 208
• Species: Rattus norvegicus
• Alignment Length: 208
• Identity: 153/208 - (73%)
• Similarity: 167/208 - (80%)
• Gaps: 2/208 - (0%)

Human     1 MWTLGRRAVAGLLASPSPAQAQTLTRVPRPAELAPLCGRRGLRTDIDATCTPRRASSNQRGLNQI 65
            |||.||||.||||.. :.::|....|.||..|....||||||....:|... |.:..|...|.||
  Rat     1 MWTFGRRAAAGLLPR-TASRASAWVRNPRGRERIGTCGRRGLHVTANADAI-RHSHLNLHYLGQI 63

Human    66 WNVKKQSVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSG 130
            .|:|||||.:::||.|||||:|.|||||.||||||||||:||||||||||||||.:|||||||.|
  Rat    64 LNIKKQSVCVVHLRNSGTLGNPSSLDETAYERLAEETLDALAEFFEDLADKPYTLKDYDVSFGDG 128

Human   131 VLTVKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLAAELTKALK 195
            |||:|||||||||||||||||||||||||||||||||||||||||||||||||||||.|||:||.
  Rat   129 VLTIKLGGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWTGKNWVYSHDGVSLHELLARELTEALN 193

Human   196 TKLDLSSLAYSGK 208
            |||||||||||||
  Rat   194 TKLDLSSLAYSGK 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	90/97 (93%)
Fxn	NP_001382061.1	mito_frataxin	92..190	CDD:132463	90/97 (93%)