Protein Alignment FXN and SPCC1183.03c

DIOPT Version :8

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_587886.1
• Gene: SPCC1183.03c / 2539143
• PomBaseID: SPCC1183.03c
• Length: 158
• Species: Schizosaccharomyces pombe
• Alignment Length: 123
• Identity: 52/124 (42%)
• Similarity: 80/124 (65%)
• Gaps: 4/124 (3%)

Human    72 SVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKL 136
            :|:.:..|....:.|.|:|.:..|.|:|::|||.|.:.||||.:: ...:|||:.:.:||:|:.|
pombe    24 NVFGLRCRYYSQVRHNGALTDLEYHRVADDTLDVLNDTFEDLLEE-VGKKDYDIQYANGVITLML 87

Human   137 GGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWT--GKNWVYSHDGVSLHELLAAELTK 192
             |:.||||||||.|..|||||||.||||.|:::  .|.|..:.|..:|..:|::|.:|
pombe    88 -GEKGTYVINKQPPAHQIWLSSPVSGPKHYEYSLKSKTWCSTRDEGTLLGILSSEFSK 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	46/100 (46%)
SPCC1183.03c	NP_587886.1	mito_frataxin	46..144	CDD:132463	46/100 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Hieranoid	1	1.000
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I1860
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0004540
OrthoInspector	1	1.000				T2523758
orthoMCL	1	0.900				OOG5_128372
Panther	1	1.100			LDO	PTHR16821
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	8	7.920