Protein Alignment FXN and fxn1

DIOPT Version :10

• Sequence 1: NP_000135.2
• Gene: FXN / 2395
• HGNCID: 3951
• Length: 210
• Species: Homo sapiens
• Sequence 2: NP_587886.1
• Gene: fxn1 / 2539143
• PomBaseID: SPCC1183.03C
• Length: 158
• Species: Schizosaccharomyces pombe
• Alignment Length: 123
• Identity: 52/123 - (42%)
• Similarity: 80/123 - (65%)
• Gaps: 4/123 - (3%)

Human    72 SVYLMNLRKSGTLGHPGSLDETTYERLAEETLDSLAEFFEDLADKPYTFEDYDVSFGSGVLTVKL 136
            :|:.:..|....:.|.|:|.:..|.|:|::|||.|.:.||||.:: ...:|||:.:.:||:|:.|
pombe    24 NVFGLRCRYYSQVRHNGALTDLEYHRVADDTLDVLNDTFEDLLEE-VGKKDYDIQYANGVITLML 87

Human   137 GGDLGTYVINKQTPNKQIWLSSPSSGPKRYDWT--GKNWVYSHDGVSLHELLAAELTK 192
             |:.||||||||.|..|||||||.||||.|:::  .|.|..:.|..:|..:|::|.:|
pombe    88 -GEKGTYVINKQPPAHQIWLSSPVSGPKHYEYSLKSKTWCSTRDEGTLLGILSSEFSK 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FXN	NP_000135.2	mito_frataxin	94..192	CDD:132463	46/99 (46%)
fxn1	NP_587886.1	mito_frataxin	46..144	CDD:132463	46/99 (46%)