Protein Alignment SEC14L2 and CG13893

DIOPT Version :10

• Sequence 1: NP_036561.1
• Gene: SEC14L2 / 23541
• HGNCID: 10699
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_612042.3
• Gene: CG13893 / 38074
• FlyBaseID: FBgn0035146
• Length: 407
• Species: Drosophila melanogaster
• Alignment Length: 402
• Identity: 126/402 - (31%)
• Similarity: 224/402 - (55%)
• Gaps: 23/402 - (5%)

Human     1 MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQKSEAMLRKHVEFRKQ 65
            |||.:.::|..|:..|.|||:.:.|.|  :...|||||:||||||.::|:.:|.|||..::.|..
  Fly     1 MSGPLPEISEEQRAILEKFRKQMDDAL--VGTHDDYFLVRWLRARKWNLEAAEKMLRASLKTRAM 63

Human    66 KDIDNIISWQPPEVIQQYLSGGMCGYDLDGCPVWYDIIGPLDAKGLLFSASKQDLLRTKMRECEL 130
            .::|||..|.||:.:|:||..|:.|||.:|.||........|..|::...::.:..:..:...|.
  Fly    64 WNVDNIEKWDPPKALQEYLPYGLMGYDNEGSPVLVCPFANFDMWGMMHCVTRFEFQKYLVLLLER 128

Human   131 LLQECAHQTTKLGRKVETITIIYDCEGLGLK-HLWKPAVEAYGEFLCMFEENYPETLKRLFVVKA 194
            .::....|:.|.|.:...:.:.:|.:.:.|| :.|:||.|.....:..:|.|:||.||..:::.|
  Fly   129 FMKIAYDQSQKHGWRARQLVVFFDMQDVNLKQYAWRPAAECVISTVKQYEANFPELLKMCYIINA 193

Human   195 PKLFPVAYNLIKPFLSEDTRKKIMVLGA---NWKEVLLKHISPDQVPVEYGGTMTDPDGNPKCKS 256
            ||||.||:|::|.||.|:|..||::..:   .|:|.|..|::....|..:||.|.|.:|:|:||:
  Fly   194 PKLFSVAFNIVKKFLDENTTSKIVIYKSGVDRWQEQLFSHVNRKAFPKAWGGEMVDRNGDPQCKA 258

Human   257 KINYGGDIPRKYYVRDQVKQQYEH---SVQISRGSSHQVEYEI-LFPGCVLRWQFMSDGADVGFG 317
            .:.:||.:|.:.|: ||..||.:.   ..|:.:|...::.::: :....:|.|:|.:...|:.||
  Fly   259 LMVWGGKLPEELYI-DQSSQQSDRDFVEAQVPKGDKLKLHFKVNVEEQKILSWEFRTFDYDIKFG 322

Human   318 IF-LKTKMGERQRAGEMTEVLPNQRYNSHLVPEDGTLTCSDPGIYVLRFDNTYSFIHAKKVNFTV 381
            |: :..|.||::....:..|..|:      :.|.|.::......|.:.|||:.|::.:||:.:.|
  Fly   323 IYSVDDKTGEKRSEVPLGTVYSNE------MDEIGYISTRPNTTYTVVFDNSASYLRSKKLRYWV 381

Human   382 EVLLPDKASEEK 393
            :::     |||:
  Fly   382 DLI-----SEEE 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SEC14L2	NP_036561.1	CRAL_TRIO_N	13..59	CDD:215024	22/45 (49%)
		SEC14	76..244	CDD:214706	52/171 (30%)
CG13893	NP_612042.3	CRAL_TRIO_N	16..57	CDD:215024	22/42 (52%)
		CRAL_TRIO	81..245	CDD:459890	48/163 (29%)
		GPCR_chapero_1	303..381	CDD:480652	21/83 (25%)