| Sequence 1: | NP_036391.1 | Gene: | HEY2 / 23493 | HGNCID: | 4881 | Length: | 337 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524513.1 | Gene: | E(spl)m8-HLH / 43161 | FlyBaseID: | FBgn0000591 | Length: | 179 | Species: | Drosophila melanogaster |
| Alignment Length: | 174 | Identity: | 48/174 - (27%) |
|---|---|---|---|
| Similarity: | 83/174 - (47%) | Gaps: | 22/174 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Human 41 TTTSQIMARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGSAKLEKAEILQMTVDHLKMLQA 105
Human 106 TGGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLSTC--------AT 162
Human 163 QREAAAMTSSM---AHHHHPLHPHHWAAAFHH----LPAALLQP 199 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HEY2 | NP_036391.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..52 | 5/10 (50%) | |
| bHLH-O_HEY2 | 40..121 | CDD:381490 | 24/79 (30%) | ||
| Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250 | 47..116 | 19/68 (28%) | |||
| ORANGE | 119..165 | CDD:128787 | 12/53 (23%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 307..337 | ||||
| YRPW motif | 327..330 | ||||
| E(spl)m8-HLH | NP_524513.1 | bHLH-O_ESM5_like | 12..70 | CDD:381486 | 18/58 (31%) |
| ORANGE | 81..125 | CDD:128787 | 11/45 (24%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||