| Sequence 1: | NP_036391.1 | Gene: | HEY2 / 23493 | HGNCID: | 4881 | Length: | 337 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_524511.1 | Gene: | E(spl)m5-HLH / 43158 | FlyBaseID: | FBgn0002631 | Length: | 178 | Species: | Drosophila melanogaster |
| Alignment Length: | 164 | Identity: | 41/164 - (25%) |
|---|---|---|---|
| Similarity: | 75/164 - (45%) | Gaps: | 25/164 - (15%) |
- Green bases have known domain annotations that are detailed below.
|
Human 38 NSPTTTSQIM-ARKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS---AKLEKAEILQMTVD 98
Human 99 HLKMLQATGGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHLST---- 159
Human 160 --CATQREAAAMTSSMAHHHHPLHPHHWAAAFHH 191 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| HEY2 | NP_036391.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..52 | 5/14 (36%) | |
| bHLH-O_HEY2 | 40..121 | CDD:381490 | 23/84 (27%) | ||
| Transcriptional repression and interaction with NCOR1 and SIN3A. /evidence=ECO:0000250 | 47..116 | 19/72 (26%) | |||
| ORANGE | 119..165 | CDD:128787 | 10/51 (20%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 307..337 | ||||
| YRPW motif | 327..330 | ||||
| E(spl)m5-HLH | NP_524511.1 | bHLH-O_ESM5_like | 20..78 | CDD:381486 | 19/63 (30%) |
| ORANGE | 87..131 | CDD:128787 | 7/45 (16%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||