Protein Alignment STK38L and wts

DIOPT Version :10

• Sequence 1: NP_055815.1
• Gene: STK38L / 23012
• HGNCID: 17848
• Length: 464
• Species: Homo sapiens
• Sequence 2: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Alignment Length: 447
• Identity: 200/447 - (44%)
• Similarity: 287/447 - (64%)
• Gaps: 38/447 - (8%)

Human    25 KLTLENFYSNLILQHEERETRQKKLEVAMEEEGLADEEKKLRRSQHARKETEFLRLKRTRLGLDD 89
            |..:|....|:|..:.:|..|:.:||..|.:.||.|:.:...|....:||:.::||||.::....
  Fly   654 KFFMEQHIENVIKSYRQRTYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSM 718

Human    90 FESLKVIGRGAFGEVRLVQKKDT-GHIYAMKILRKSDMLEKEQVAHIRAERDILVEADGAWVVKM 153
            |..||.||.||||||.||.|.|| .|:||||.|||:|:|::.||||::||||||.|||..||||:
  Fly   719 FVKLKPIGVGAFGEVTLVSKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKL 783

Human   154 FYSFQDKRNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYISETVLAIDAIHQLGFIHRDIKPDN 218
            :||||||.|||.:|:::||||:|:||:|.....||..:|||:|...|:|::|::|||||||||||
  Fly   784 YYSFQDKDNLYFVMDYIPGGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDN 848

Human   219 LLLDAKGHVKLSDFGLCTGLKKAHRTEFYRNLTHNPPSDFSFQNMNSKRK--AETWKK------- 274
            :|:|..||:||:|||||||.:..|.:::|:            :|.|..|:  .|.|::
  Fly   849 ILIDRDGHIKLTDFGLCTGFRWTHNSKYYQ------------ENGNHSRQDSMEPWEEYSENGPK 901

Human   275 -----------NRRQLAYSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETP 328
                       ::|.||:|.||||:||||||..::||.:|||:||:|||:||||:|.|||.:.:|
  Fly   902 PTVLERRRMRDHQRVLAHSLVGTPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSP 966

Human   329 QETYRKVMNWKETLVFPPEVPISEKAKDLILRFCIDSENRIGNSGVEEIKGHPFFEGVDWEHIRE 393
            .||.:||:||::||..||:..:|.:|.|||.|.|..::.|:|.| |:|:|.|.||:|:|:..:|:
  Fly   967 LETQQKVINWEKTLHIPPQAELSREATDLIRRLCASADKRLGKS-VDEVKSHDFFKGIDFADMRK 1030

Human   394 RPAAIPIEIKSIDDTSNFDDF-PESDILQPVPNTTEPDYKSKDWV---FLNYTYKRF 446
            :.|....|||...||||||.. ||.........::..|....|..   |..:|::||
  Fly  1031 QKAPYIPEIKHPTDTSNFDPVDPEKLRSNDSTMSSGDDVDQNDRTFHGFFEFTFRRF 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK38L	NP_055815.1	MobB_NDR_LATS-like	12..86	CDD:459252	19/60 (32%)
		S100B binding. /evidence=ECO:0000250	63..88		7/24 (29%)
		STKc_NDR2	87..452	CDD:270776	181/385 (47%)
wts	NP_733403.1	MobB_LATS1	644..718	CDD:439273	19/63 (30%)
		STKc_LATS	717..1078	CDD:270749	177/373 (47%)