Protein Alignment: ALDH1B1 and CG31075

• Sequence 1: NP_000683.3
• Gene: ALDH1B1
• HGNCID: 407
• Length: 517
• Species: Homo sapiens
• Sequence 2: NP_001247324.1
• Gene: CG31075
• FlyBaseID: FBgn0051075
• Length: 508
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 287/512 (56%)
• Similarity: 372/512 (73%)
• Gaps: 8/512 (2%)

Human     2 LRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIG 66
            |:.|....|::..:.:::....|...|      .|.|||||||:.|:||.|||.|.||.|.:.|.
  Fly     5 LQKLLAHQLAVSRKWSKFDHTYAQCEP------NYCQLFINNEFVDSVSGKTFATFNPATSKEIV 63

Human    67 HVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNRLADLVERDRVYLASLETLDNGKPF 131
            .|:|||:||:|.|||||::||...|.||::...:|..|:|:|..|::||:.:||||||.|||||:
  Fly    64 QVSEGDKADIDLAVKAAKKAFHRDSEWRKLSPLQRTNLMNKLCALMDRDKAFLASLETQDNGKPY 128

Human   132 QESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKL 196
            .|: ..|:...|...:|:|||.||:.|.|||..| ....||.|||||.|||||||:||:|..||.
  Fly   129 AEA-LFDVTYSILTLQYYAGWTDKFFGDTIPAGG-FVSMTRKEPVGVVGQIIPWNYPLLMLAWKW 191

Human   197 APALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFT 261
            .||||.|.|::||.||||||:||::|:|.||||||.||:|::.|:||||||||:.|.|:.|||||
  Fly   192 GPALAVGCTIIMKPAEQTPLTALHMAALAKEAGFPAGVINVVNGFGPTAGAAISAHPDIAKVAFT 256

Human   262 GSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTF 326
            ||.|:|.::.:||..||||||:||||||||.:|..|||::.|||..|||||.|.||.|||||||:
  Fly   257 GSVEIGRIVMQAAATSNLKRVSLELGGKSPVVVFDDADIDFAVETTHEALFSNHGQSCCAGSRTY 321

Human   327 VEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERF 391
            |.|.||:||:.:...|||.||||||||.:.|||||:|.:...:|||||:.|:||||||..||:|.
  Fly   322 VHEKIYDEFVAKAAAKAKARKVGNPFEQNVQQGPQIDDDMLTKVLGYIESGKKEGAKLQAGGKRI 386

Human   392 GERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKA 456
            |..|||::||||..|:||||||:||||||||.:|||..:||:::||||.:|||||.|.|.|::||
  Fly   387 GNVGFFVEPTVFSDVKDDMRIAQEEIFGPVQSIFKFSSLEEMIDRANNVQYGLAAGVITNDINKA 451

Human   457 MYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKV 512
            :.|...:.||:||:|.|:.|...|||||:|.||.|||||:|||..|.|.||:|:|:
  Fly   452 LKFANNVDAGSVWINCYDAVLPSTPFGGYKHSGIGRELGKDGLDNYLETKTITMKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALDH1B1	NP_000683.3	ALDH_F1AB_F2_RALDH1	31..511	CDD:143459	281/480 (59%)
CG31075	NP_001247324.1	ALDH-SF	33..506	CDD:299846	281/475 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C99482970
eggNOG	1	0.900				E1_COG1012
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000142
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900				OOG5_126638
Panther	1	1.100			O	PTHR11699
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.830