Protein Alignment ACSL3 and Acsx1L

DIOPT Version :10

• Sequence 1: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_650828.1
• Gene: Acsx1L / 42351
• FlyBaseID: FBgn0038730
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 108/496 - (21%)
• Similarity: 184/496 - (37%)
• Gaps: 156/496 - (31%)

Human   196 PAIVHALNETEVTNIITSKELLQTKLK-------------DIVSLVPR-LRHIITVDGKPPTWSE 246
            |.:...::.||.| ::|..|||...::             |||.::.| ..|::.|     .::.
  Fly    43 PQLTAQISATEGT-VLTRGELLANAMRLASYMRSLGLLQSDIVGIIGRNTTHMLAV-----AYAC 101

Human   247 FPKGIIVHTM--------------------------------AAVEALGAK-ASMENQP------ 272
            |..||..|::                                :|...|..| .:|.|.|
  Fly   102 FFNGIAFHSLNITYDRDTIEKIYKVTRPSIIFCDGDEFEKVRSATAELDVKIVTMRNHPLDSIKI 166

Human   273 ---HSKPLPSDI------------AVIMYTSGSTGLPKGVMISHS-NIIAGITGMAERIPELGEE 321
               .:.|:..:.            ..|:.:||:||.||.|.|::| :|:||..       .|...
  Fly   167 DEVVATPIEENFQPAKLEKGNDQTLAILCSSGTTGTPKAVTITNSRHILAGNY-------HLTTA 224

Human   322 DVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ------SSKIKKGSKGDTSMLKPTLM 380
            ||...:..|..:..|   |..::.|.   :|:.:.:||.      :.:|.:..|...::..|:.|
  Fly   225 DVQYSHNTLDWITGL---LTTITSGV---FSTTRIIADNAFDPAFALRIIEEYKVTWTIQPPSSM 283

Human   381 AAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPL---CDSFVFRKVRSLLG 442
            |.:....|       .:..:|||.:  .::...:....::.||..:.|   |..||
  Fly   284 ALMINCPD-------FETCDMSSLR--CYMFGGSRAALEVQKGIRSRLSHDCLQFV--------- 330

Human   443 GNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIK 507
                                            ||.||.....||:..:|..||.||..:...::|
  Fly   331 --------------------------------YGFTELGAMATINCHFDEKTGSVGQLVNGLKMK 363

Human   508 LKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDG 572
            :.| ::|.....|:   .||:.|.......|||.||.:|:.  ..|..|  |..:||:|..:.||
  Fly   364 IIN-DDGESLGPDE---IGEVCIMNNQHWSGYYGNEVETRN--MRDSLG--WYHSGDLGYMDRDG 420

Human   573 CLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAY 613
            .|.|:||||:::|.|...|.. ..:|:.:..:|.|..:|.:
  Fly   421 FLYIMDRKKEMLKYQNIMYYP-NDIESVISEMPQVAEVCVF 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	108/496 (22%)
Acsx1L	NP_650828.1	Firefly_Luc_like	47..522	CDD:341237	107/492 (22%)