Protein Alignment ACSL3 and CG9993

DIOPT Version :10

• Sequence 1: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_611518.1
• Gene: CG9993 / 37358
• FlyBaseID: FBgn0034553
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 517
• Identity: 118/517 - (22%)
• Similarity: 195/517 - (37%)
• Gaps: 174/517 - (33%)

Human   157 KPKTNIAIFCE-TRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTK 220
            |||   .|||: ...:.:.|.::...:..:::.|..||.|           |.||   ::||
  Fly   125 KPK---VIFCDLDNYQTLSAVKSSLKFKTEIILLTGTLPG-----------VRNI---QDLL--- 169

Human   221 LKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIM 285
                            .||        ..|....|:.|.            ||.  ...|.|.|:
  Fly   170 ----------------ADG--------CTGYDEKTLFAC------------PHL--CGDDTAFII 196

Human   286 YTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEED-VYIGYLPLAHVLELSAELVCLSHGCRI 349
            .:||.|||||||..||.:::     .:.:||:|...| |...:.||..:..:...|..|.:|||.
  Fly   197 TSSGVTGLPKGVTRSHRSLL-----NSAKIPQLFTSDTVLFCFSPLYWISCIFTLLASLVNGCRR 256

Human   350 GYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYN 414
            ..::                      :|..:|...::::|      ::||.:.:...::.:||.:
  Fly   257 IITN----------------------RPFSVAYFADLVER------HQVSFVLTVPHHMALLAKS 293

Human   415 YKMEQIS-----------KGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFC 468
            .:.::::           .|...|:   .::|::..|||.|                ||..:
  Fly   294 PERQELAAKMQCVQSFVCSGSKVPM---GIWRQLYELLGAN----------------RFAVL--- 336

Human   469 CPVGQGYGLTESAGAGTISEVWDYNTGRVGAPL-----VCCEIKLKNWEEGGYFNTDKPHPRGEI 528
                  |||||:.|   ||:       .||.||     :...::::..:..|  .:..|:..|:|
  Fly   337 ------YGLTETGG---ISK-------NVGGPLGSEGRLLRNVQVRVVDPHG--QSLGPNQTGQI 383

Human   529 LIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKL------- 586
            |:.......|||.|..:|:.....|   .:||.|||.|.|:.:|||....|..|:.|.
  Fly   384 LVRLNLRWGGYYHNPQETQVTVTPD---GKWLLTGDHGYFDDEGCLHFQSRDTDVFKYNHFPIYP 445

Human   587 QAGEYVSL---GKVEAALKNLP--LVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKG 643
            :..|.|.|   |..|.|:..:|  :..|:.|.|          ||.|:.||.....:..:||
  Fly   446 KQIEDVILHLPGVHEVAVFGIPDEVSTNLTACA----------VVRNEDELGAQLTEADVKG 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	118/517 (23%)
CG9993	NP_611518.1	Firefly_Luc_like	44..528	CDD:341237	118/517 (23%)