Protein Alignment ACSL3 and CG17999

DIOPT Version :10

• Sequence 1: NP_004448.2
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 120/548 - (21%)
• Similarity: 198/548 - (36%)
• Gaps: 152/548 - (27%)

Human   119 PNGKIF--KKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFM 181
            |.||.|  .::.||        :|.:|.... |..|::.         .|:|..:.:..||.. .
  Fly    17 PRGKDFYGPEMTLG--------EVIMRVLQI-NADQVMQ---------ICDTTGQELTGAQLA-Q 62

Human   182 YNFQLVTLYATLG---GPAI-VHALNETEVTNIITS------------KELLQTKLKDIVSLV-P 229
            .:.::...:..||   |..: :.|.|.|.:|::|.:            .|..:..:|.:..:. |
  Fly    63 QSARIAQAFKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEP 127

Human   230 RL-------RHII-TVDGK--PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLP----SD 280
            ::       .||| ||:||  .|.......|.:...:...|.|..:.|:....: .|.|    ..
  Fly   128 KVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAAY-VPCPKLHGDH 191

Human   281 IAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEED-VYIGYLPLAHVLELSAELVCLS 344
            .|.|:.:||:||:||||..||.:::...     :.|.....| |.:.:.||..:......|..|.
  Fly   192 TAFIVCSSGTTGMPKGVTRSHRSLLCNC-----KNPNTYTRDSVLLSFSPLYWISGTIILLASLL 251

Human   345 HGC-RIGYSSP-------QTLADQ--------SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKN 393
            :|| ||..:.|       |.:|..        |.:|...||.|:                    :
  Fly   252 NGCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDS--------------------D 296

Human   394 VMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSAT 458
            ||...:::.|.              ::..|..:.:|.: |.|::..|:|
  Fly   297 VMELKAQLQSI--------------RVLIGAGSKVCKA-VCRRMYELIG---------------- 330

Human   459 TQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPH 523
            .|||:         .||||:|..|.          :..||.|:.|....::|.|.........|.
  Fly   331 NQRFV---------VGYGLSEMGGL----------SKNVGGPVGCEGKVMRNVELRVLDKLKMPL 376

Human   524 PRGEILIGGQSVTM---GYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVK 585
            ...|:.|....:..   |||:|...|:.....|   ..|..|||||..:.:|.|.|..|..|:.|
  Fly   377 GINEVGIIYARLRFKWAGYYRNPEATRRALSSD---GMWFRTGDIGYLDSEGYLYIQTRDTDVFK 438

Human   586 LQAGEYVSLGKVEAALKNLPLVDNICAY 613
            ....: :...::|..:..||.|...|.:
  Fly   439 FNNFQ-IYPEQIEEFILRLPGVSEACVF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_004448.2	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	120/548 (22%)
CG17999	NP_611517.1	Firefly_Luc_like	45..529	CDD:341237	110/511 (22%)