Protein Alignment ACSL3 and CG17999

DIOPT Version :9

• Sequence 1: NP_001341087.1
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Sequence 2: NP_611517.1
• Gene: CG17999 / 37357
• FlyBaseID: FBgn0034552
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 120/548 - (21%)
• Similarity: 198/548 - (36%)
• Gaps: 152/548 - (27%)

Human   119 PNGKIF--KKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFM 181
            |.||.|  .::.||        :|.:|.... |..|::.         .|:|..:.:..||.. .
  Fly    17 PRGKDFYGPEMTLG--------EVIMRVLQI-NADQVMQ---------ICDTTGQELTGAQLA-Q 62

Human   182 YNFQLVTLYATLG---GPAI-VHALNETEVTNIITS------------KELLQTKLKDIVSLV-P 229
            .:.::...:..||   |..: :.|.|.|.:|::|.:            .|..:..:|.:..:. |
  Fly    63 QSARIAQAFKRLGLRRGDVVGISANNSTYLTSVIIAALLRGIPINPLHPEFTEETVKYMYDITEP 127

Human   230 RL-------RHII-TVDGK--PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLP----SD 280
            ::       .||| ||:||  .|.......|.:...:...|.|..:.|:....: .|.|    ..
  Fly   128 KVIFCDVENYHIIKTVNGKLQNPAKIYLVNGKLEGVLDISEMLNDEDSITAAAY-VPCPKLHGDH 191

Human   281 IAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEED-VYIGYLPLAHVLELSAELVCLS 344
            .|.|:.:||:||:||||..||.:::...     :.|.....| |.:.:.||..:......|..|.
  Fly   192 TAFIVCSSGTTGMPKGVTRSHRSLLCNC-----KNPNTYTRDSVLLSFSPLYWISGTIILLASLL 251

Human   345 HGC-RIGYSSP-------QTLADQ--------SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKN 393
            :|| ||..:.|       |.:|..        |.:|...||.|:                    :
  Fly   252 NGCRRIITNRPYSVEYLLQLVARHKVTFLFLASHQIALLSKHDS--------------------D 296

Human   394 VMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSAT 458
            ||...:::.|.              ::..|..:.:|.: |.|::..|:|
  Fly   297 VMELKAQLQSI--------------RVLIGAGSKVCKA-VCRRMYELIG---------------- 330

Human   459 TQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPH 523
            .|||:         .||||:|..|.          :..||.|:.|....::|.|.........|.
  Fly   331 NQRFV---------VGYGLSEMGGL----------SKNVGGPVGCEGKVMRNVELRVLDKLKMPL 376

Human   524 PRGEILIGGQSVTM---GYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVK 585
            ...|:.|....:..   |||:|...|:.....|   ..|..|||||..:.:|.|.|..|..|:.|
  Fly   377 GINEVGIIYARLRFKWAGYYRNPEATRRALSSD---GMWFRTGDIGYLDSEGYLYIQTRDTDVFK 438

Human   586 LQAGEYVSLGKVEAALKNLPLVDNICAY 613
            ....: :...::|..:..||.|...|.:
  Fly   439 FNNFQ-IYPEQIEEFILRLPGVSEACVF 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACSL3	NP_001341087.1	AFD_class_I	30..717	CDD:418409	120/548 (22%)
CG17999	NP_611517.1	CaiC	25..545	CDD:223395	116/540 (21%)
		AFD_class_I	38..529	CDD:302604	112/519 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149095
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840