DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX3 and COX3

DIOPT Version :9

Sequence 1:	YP_009047271.1	Gene:	COX3 / 19893540	FlyBaseID:	FBgn0013676	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_009328.1	Gene:	COX3 / 854627	SGDID:	S000007283	Length:	269	Species:	Saccharomyces cerevisiae

Alignment Length:	267	Identity:	116/267 - (43%)
Similarity:	160/267 - (59%)	Gaps:	12/267 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 STHSNHPFHLVDYSPWP-------LTGAIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWW 59
            |.|..||||:|..||||       |:.|:....|:.|.:...:...::||||     :.:...|:
Yeast     7 SRHQQHPFHMVMPSPWPIVVSFALLSLALSTALTMHGYIGNMNMVYLALFVL-----LTSSILWF 66

  Fly    60 RDVSREGTYQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIIS 124
            ||:..|.||.|.||.||..|:..|.::|:|||||.|...|||:|||::||.:.|||.|||:||.:
Yeast    67 RDIVAEATYLGDHTMAVRKGINLGFLMFVLSEVLIFAGLFWAYFHSAMSPDVTLGACWPPVGIEA 131

  Fly   125 FNPFQIPLLNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTI 189
            ..|.::|||||.|||:||.|||::||:|:..|.::...||..|..|.:.|...|..||..|.|||
Yeast   132 VQPTELPLLNTIILLSSGATVTYSHHALIAGNRNKALSGLLITFWLIVIFVTCQYIEYTNAAFTI 196

  Fly   190 ADSIYGSTFFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLY 254
            :|.:|||.|:..||.|.:|:::....|.|...|..|.|.:..||.|:|....|.|.:||:|||||
Yeast   197 SDGVYGSVFYAGTGLHFLHMVMLAAMLGVNYWRMRNYHLTAGHHVGYETTIIYTHVLDVIWLFLY 261

  Fly   255 ITIYWWG 261
            :..||||
Yeast   262 VVFYWWG 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX3	YP_009047271.1	COX3	4..258	CDD:214439	111/260 (43%)
COX3	NP_009328.1	COX3	12..269	CDD:395410	114/262 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346504
Domainoid	1	1.000	239	1.000	Domainoid score	I377
eggNOG	1	0.900	-	-		E1_COG1845
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	242	1.000	Inparanoid score	I684
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62397
OrthoFinder	1	1.000	-	-		FOG0003223
OrthoInspector	1	1.000	-	-		oto99665
orthoMCL	1	0.900	-	-		OOG6_104028
Panther	1	1.100	-	-	LDO	PTHR11403
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R246
SonicParanoid	1	1.000	-	-		X2639
TreeFam	1	0.960	-	-
	14	13.790