DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment COX3 and COX3

DIOPT Version :9

Sequence 1:	YP_009047271.1	Gene:	COX3 / 19893540	FlyBaseID:	FBgn0013676	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_904334.1	Gene:	COX3 / 17710	MGIID:	102502	Length:	261	Species:	Mus musculus

Alignment Length:	259	Identity:	172/259 - (66%)
Similarity:	203/259 - (78%)	Gaps:	0/259 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 THSNHPFHLVDYSPWPLTGAIGAMTTVSGMVKWFHQYDISLFVLGNIITILTVYQWWRDVSREGT 67
            ||..|.:|:|:.||||||||..|:...||:|.|||...|:|..||.:..|||:|||||||.||||
Mouse     2 THQTHAYHMVNPSPWPLTGAFSALLLTSGLVMWFHYNSITLLTLGLLTNILTMYQWWRDVIREGT 66

  Fly    68 YQGLHTYAVTIGLRWGMILFILSEVLFFVSFFWAFFHSSLSPAIELGASWPPMGIISFNPFQIPL 132
            |||.||..|..|||:||||||:|||.||..|||||:||||.|..:||..|||.||...||.::||
Mouse    67 YQGHHTPIVQKGLRYGMILFIVSEVFFFAGFFWAFYHSSLVPTHDLGGCWPPTGISPLNPLEVPL 131

  Fly   133 LNTAILLASGVTVTWAHHSLMENNHSQTTQGLFFTVLLGIYFTILQAYEYIEAPFTIADSIYGST 197
            |||::||||||::|||||||||...:...|.|..|::||:|||||||.||.|..|:|:|.|||||
Mouse   132 LNTSVLLASGVSITWAHHSLMEGKRNHMNQALLITIMLGLYFTILQASEYFETSFSISDGIYGST 196

  Fly   198 FFMATGFHGIHVLIGTTFLLVCLLRHLNNHFSKNHHFGFEAAAWYWHFVDVVWLFLYITIYWWG 261
            |||||||||:||:||:|||:|||||.|..||:..|||||||||||||||||||||||::|||||
Mouse   197 FFMATGFHGLHVIIGSTFLIVCLLRQLKFHFTSKHHFGFEAAAWYWHFVDVVWLFLYVSIYWWG 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
COX3	YP_009047271.1	COX3	4..258	CDD:214439	166/253 (66%)
COX3	NP_904334.1	COX3	1..261	CDD:177161	172/259 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850070
Domainoid	1	1.000	385	1.000	Domainoid score	I812
eggNOG	1	0.900	-	-		E1_COG1845
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	390	1.000	Inparanoid score	I1981
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62397
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003223
OrthoInspector	1	1.000	-	-		oto93676
orthoMCL	1	0.900	-	-		OOG6_104028
Panther	1	1.100	-	-	LDO	PTHR11403
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R246
SonicParanoid	1	1.000	-	-		X2639
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.790