Protein Alignment CG45065 and chdh

DIOPT Version :10

• Sequence 1: NP_001285251.1
• Gene: CG45065 / 19835504
• FlyBaseID: FBgn0266435
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_002663301.2
• Gene: chdh / 100331020
• ZFINID: ZDB-GENE-120111-1
• Length: 585
• Species: Danio rerio
• Alignment Length: 633
• Identity: 236/633 - (37%)
• Similarity: 328/633 - (51%)
• Gaps: 104/633 - (16%)

  Fly     3 FGTMTSLLGMI--PLLAIGMNFYRYQSVDPENKVQEPTVIRR---QYDFVVIGGGSAGAVVANRL 62
            |.:.|.|:..:  |||     .:||.|          ||:.:   .|.:|::|.||||.|:|:||
Zfish     4 FSSSTRLMSSLCSPLL-----HHRYIS----------TVVNKNTPSYSYVIVGAGSAGCVLASRL 53

  Fly    63 SEVRNWTVLLLEAGGDETEISDVPALAGYLQLTELDWKYQTTPSSTRQYC------------QAM 115
            :|..:.:|||||||..:.          :|..|.|.||.....:.|...|            ||.
Zfish    54 TENPSDSVLLLEAGPKDK----------HLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLPQAH 108

  Fly   116 KGDR-CFWPRGKVLGGSSVLNAMVYVRGSKNDYNHWASLGNPGWDYDSMLKYFLKSEDVRNPYLA 179
            ..|| .:||||:|.||||.||||||:||...|||.|.|.|..||:||..|.||.|::.
Zfish   109 MDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQT------- 166

  Fly   180 KTPYHETG--------GYLTVQEAPWRTPLSIAFLQAGIEMGYE-NRDINGAQQTGFMLTQSTIR 235
                ||.|        |.|.|.....:.||..||:|||.:.||. ..|:||.||.|......||.
Zfish   167 ----HELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVGWMDMTIH 227

  Fly   236 RGARCSTGKAFIRPVRQRKNFDVLLHAEATRILFDKQKRAIGVEYMRGGRKNVVFVRREVIASAG 300
            :|.|.||..|::||...|.|....:....||:||| ..||.||||.:.|:...||..:|||.|.|
Zfish   228 KGQRWSTASAYLRPALSRPNLSTEVRCMVTRVLFD-GARARGVEYQQNGQIKKVFAEKEVILSGG 291

  Fly   301 ALNTPKLLMLSGVGPAEHLQEHNIPVISDLP-VGNNMQDHVGLGGLTFVVDA---PLTVTRNR-- 359
            |:|:|:||:|||||.|:.|:..:|||:..|| ||.|:|||:.|    :|..|   |:|:.|.:
Zfish   292 AINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLEL----YVQHACTQPITLYRAQKP 352

  Fly   360 FQTIPVSMEYILRERGPMTFSGVEGVAFLNTKYQDPSVDWPDVQFHFCPSSINSDGGEQIRKILN 424
            .|.:.:.:|::|:..|....:.:|...|:.::   |.|..||:||||.||.: .|.|....||
Zfish   353 LQMLKIGLEWLLKFTGYGATAHLESGGFIRSR---PDVPHPDIQFHFLPSQV-IDHGRVSSKI-- 411

  Fly   425 LRDGFYNTVYKPLQHSETWSILPLLLRPKSTGWVRLNSRNPQHQPKIIPNYFAHQEDIDVLVEGI 489
                            |.:.:....:|..|.||::|.|::|:..|.:.|||.:.:.|:....|.:
Zfish   412 ----------------EAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECV 460

  Fly   490 KLAINVSNTQAFQRF-GSRLHNIPLPGCRHLPFQSNEYWACCIKEFTFTIYHPAGTCRMGPSWDV 553
            :|...:...|||..| |..:.  |.|.     .||:......:::...:.|||:.||:||...|.
Zfish   461 RLTREIFAQQAFDEFRGPEVQ--PGPA-----VQSDAEIDAFVRQKADSAYHPSCTCKMGRPEDR 518

  Fly   554 TAVVDPRLRVYGVSGVRVVDASIMPTIVNGNPNAPVIAIGEKASDLIK 601
            .|||.|.|||:||.|:||||||:||::|:||.|||.|.|.|||:|.||
Zfish   519 MAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAIK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45065	NP_001285251.1	BetA	43..603	CDD:441878	225/588 (38%)
chdh	XP_002663301.2	PRK02106	30..585	CDD:235000	225/592 (38%)