DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG45071 and madf-4

DIOPT Version :9

Sequence 1:	NP_730024.1	Gene:	CG45071 / 19834908	FlyBaseID:	FBgn0266441	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_505565.3	Gene:	madf-4 / 179386	WormBaseID:	WBGene00011575	Length:	329	Species:	Caenorhabditis elegans

Alignment Length:	273	Identity:	57/273 - (20%)
Similarity:	99/273 - (36%)	Gaps:	57/273 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IHDIEERPAIWNRNFHCNKA--FLEQMWDELS---GAHKLPKIVLKAKWKGLRDNFRVEYKRIPR 75
            |..::..|.::||....:|.  :..::|..:|   |....| :.|:.|||.:||    :|.|:.:
Worm    23 IDSVQRNPCVYNRYDPLHKVTDYKHEIWKLISIEIGYDGQP-VELERKWKHMRD----KYVRLRK 82

  Fly    76 ADNGDFMVDPATFESKWLHYY-ALLFLTDHMRHRLPKNEQDQSFYFSQQSED------------C 127
            .|.   ...|....:||.:|| .:.||..::.||..|.::|   |.:..:.|            .
Worm    83 QDK---QKAPIKKTNKWYNYYHKMSFLDPYVEHRNRKRQKD---YLNSNTPDFLDDDTAFLDGLS 141

  Fly   128 EKTVVEPDLTNGLIRRLQDSDEDYDEEEMEADGEASEATMEETMPTPPAAHQMNQVSTTPLATG- 191
            .|.:::|:      ..|..:|..|:.....:...:|.:.........|.....:......|...
Worm   142 VKEMLKPE------SLLTSNDAGYNSPHTTSSSSSSGSNNNGRFLDSPTIDIEDDKKNLALIYDK 200

  Fly   192 --ALRAQEEAHQHALIKAG---LLRAQLMELEKEA-------EDLSRKP---------PPPQQMT 235
              |.:.:.|.:.....|.|   |.......:||.|       ....|||         ||||:..
Worm   201 FVANQTENEKNHRFSNKHGKDLLFSTTNTLIEKLATTSTAPSSSRKRKPIPVQILPSSPPPQEKN 265

  Fly   236 SPVAPSLQVLVEP 248
            :.:.....:|.||
Worm   266 TKIELLEDILNEP 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG45071	NP_730024.1	MADF	14..106	CDD:214738	25/95 (26%)
CG45071	NP_730024.1	BESS	384..418	CDD:281011
madf-4	NP_505565.3	MADF	22..111	CDD:214738	25/95 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100