DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ceh-13 and ey

DIOPT Version :9

Sequence 1:	NP_498655.1	Gene:	ceh-13 / 176069	WormBaseID:	WBGene00000437	Length:	202	Species:	Caenorhabditis elegans
Sequence 2:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	54/216 - (25%)
Similarity:	82/216 - (37%)	Gaps:	70/216 - (32%)

- Green bases have known domain annotations that are detailed below.

Worm    16 QDWPTTH---SYYPS----VPSSYSPLNHHPADIWAAHPSNYIMGNGHVSPPATASGLSPP---- 69
            |.||..|   |:||:    :|.|.:|              |......:.|.|:.|..||||
  Fly   358 QSWPPRHYSGSWYPTSLSEIPISSAP--------------NIASVTAYASGPSLAHSLSPPNDIE 408

Worm    70 ----------------------------ASRSSNSSAELPTGVTASQHNTYKWMHTKRSQRPAAP 106
                                        :..:.:...|...|..::..|      |:..|.....
  Fly   409 SLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEGENSNGGASNIGN------TEDDQARLIL 467

Worm   107 KKKVIDENGTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKIWFQNRRMKEKK 171
            |:|:    ..|||:||..|:..|||||....|.:...|..:|..:.|.||::::||.|||.|.::
  Fly   468 KRKL----QRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRR 528

Worm   172 REKEKAFLARNTWESNSPTSS 192
            .||     .||  :..:|.|:
  Fly   529 EEK-----LRN--QRRTPNST 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ceh-13	NP_498655.1	Homeobox	118..164	CDD:278475	18/45 (40%)
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	22/51 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910