DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ceh-13 and en

DIOPT Version :9

Sequence 1:	NP_498655.1	Gene:	ceh-13 / 176069	WormBaseID:	WBGene00000437	Length:	202	Species:	Caenorhabditis elegans
Sequence 2:	NP_523700.2	Gene:	en / 36240	FlyBaseID:	FBgn0000577	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	61/200 - (30%)
Similarity:	90/200 - (45%)	Gaps:	22/200 - (11%)

- Green bases have known domain annotations that are detailed below.

Worm     2 SSTECYGAPPHNYYQDWPTTHSYYPSVPSS-------YSPLNHHPADIWAAHPSNYIMGNGHVSP 59
            |::.....||.:......:|.|...|..||       .|.||..|:....|..|.....:....|
  Fly   322 SASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQP 386

Worm    60 PATASGLSPPASRSSNSSAELPTGVTASQHNTYK----WMH-TKRSQRPAA---------PKKKV 110
            ....|.:|..:...|:......||.|.::....:    |:: |:.|.||::         ||.|.
  Fly   387 IPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKT 451

Worm   111 IDENGTNRTNFTTHQLTELEKEFHTAKYVNRTRRTEIASNLKLQEAQVKIWFQNRRMKEKKREKE 175
            .||. ..||.|::.||..|::||:..:|:...||.:::|.|.|.|||:||||||:|.|.||....
  Fly   452 NDEK-RPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGS 515

Worm   176 KAFLA 180
            |..||
  Fly   516 KNPLA 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ceh-13	NP_498655.1	Homeobox	118..164	CDD:278475	21/45 (47%)
en	NP_523700.2	Homeobox	457..510	CDD:278475	25/52 (48%)
en	NP_523700.2	Engrail_1_C_sig	512..541	CDD:287495	2/8 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910