Protein Alignment Mpo and cd

DIOPT Version :10

• Sequence 1: NP_034954.2
• Gene: Mpo / 17523
• MGIID: 97137
• Length: 718
• Species: Mus musculus
• Sequence 2: NP_651081.1
• Gene: cd / 42681
• FlyBaseID: FBgn0263986
• Length: 830
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 244/728 - (33%)
• Similarity: 342/728 - (46%)
• Gaps: 140/728 - (19%)

Mouse    37 LSCMEEAKQLVDRAYKERRESIKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLLK 101
            ||...||::|..|.|.|.:.:|                                       |:.|
  Fly   156 LSTNPEARKLARRGYVENQATI---------------------------------------DIAK 181

Mouse   102 RKLQPLWPRPFNVTDVLTPAQLNLLSVSSGCAYQDV-------RVTCPPNDKYRTITGHCNNRRS 159
            |         ||.|.  .|.:.|:     |...:.|       |:.|..|.:||..||.|||::.
  Fly   182 R---------FNYTK--QPGRSNI-----GWGPKIVLPDPTVLRLECDFNARYRRSTGVCNNKQH 230

Mouse   160 P-TLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERA 223
            | |.|||...:.|.:..:|.||::     .|.|:.:| ::|.|||||..|.|   .....|....
  Fly   231 PRTYGASMVPYRRMVSPDYADGIA-----APRVSHHG-RLPPARQVSLKIHR---SSYETDSNFT 286

Mouse   224 LMFMQWGQFLDHDITLTPEPATRFSFFTGLNCET--SCL-----QQPPCFPLKIPPNDPRIKNQK 281
            :|...:|||:|||||.|       |..|....|:  .|:     |.|.|:|:.|.|:||..|...
  Fly   287 VMLAVFGQFMDHDITAT-------SLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYYKQYN 344

Mouse   282 -DCIPFFRSCPACTRNNITIRNQINALTSFVDASGVYGSEDPLARKLRNLTNQLGLLAINTRFQD 345
             .|:.|.||.||.| .....|.|:|..|:|:|||.|||:.:....:||:..|.    ::.....|
  Fly   345 ISCMNFVRSAPAPT-GRFGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFING----SLRMFVTD 404

Mouse   346 NGRALMPFDSLHDDPCLLTNR--SARIP--CFLAGDMRSSEMPELTSMHTLFVREHNRLATQLKR 406
            :||.|:|..|...|.|   ||  ..|:.  ||.:||.|::|...|||||.|:.|.||.||.||:.
  Fly   405 DGRQLLPISSNPADGC---NRVQMTRLGKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQE 466

Mouse   407 LNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGP--AAMKKYLPQYR------SYNDSVDPR 463
            .||.|..|:||||||||:||.:..|||.::||::||.  :..|..||...      :|:..|||.
  Fly   467 QNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTYDPEVDPS 531

Mouse   464 IANVF-TNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVPLSKVFFASWRVVLEGGIDPILRGLMAT 527
            |||.| ..|||:.|||: |.:|.::   |.......:.|.|:.|..:.:..|.|||..|.....|
  Fly   532 IANCFAAAAFRFAHTLL-PGLFNIS---RDNSTPEAIELHKMLFNPFSLWAEHGIDHALMTAANT 592

Mouse   528 PAKLNRQNQIVVD-----EIRERLFE-----QVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGL 582
            |.       :.||     |:.::|||     :|...||||.:||:||.||||:|.|..:||.|.|
  Fly   593 PV-------MQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRL 650

Mouse   583 PQPSTVGELGTVLKN--LELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRK 645
            |...|..|:...:.|  |:..|::   |.:|.::|::.|.:|||.......|.||:|::..||.:
  Fly   651 PTVDTWEEMSQAIDNATLDSIRQI---YESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLR 712

Mouse   646 LRDGDRFWWE---NPGVFSKQQRQALASISLPRIICDNT-GITTVSKNNIFMSNTYPRDFVSCNT 706
            |:.||..|:|   .|..|:|.|...:...||..|||.|: |||.|.::.:..........|.|..
  Fly   713 LKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHVDCQD 777

Mouse   707 LP--KLNLTSWKE 717
            |.  ..|...|.|
  Fly   778 LEGFHFNFEPWSE 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mpo	NP_034954.2	myeloperoxidase_like	289..702	CDD:188656	162/441 (37%)
cd	NP_651081.1	An_peroxidase	218..762	CDD:460804	216/581 (37%)