DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UBL4B and CG31528

DIOPT Version :9

Sequence 1:	NP_981957.1	Gene:	UBL4B / 164153	HGNCID:	32309	Length:	174	Species:	Homo sapiens
Sequence 2:	NP_730833.1	Gene:	CG31528 / 318785	FlyBaseID:	FBgn0051528	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	33/170 - (19%)
Similarity:	63/170 - (37%)	Gaps:	48/170 - (28%)

- Green bases have known domain annotations that are detailed below.

Human    16 KVSGQESVATLKR---------LVSRRLKVPEEQQHLLFRGQLLEDDKHLSDYCIGPNASINVIM 71
            |.||:....||::         ||:.|.:....:..|:|.||:|.|:..:....|....:::|:.
  Fly    12 KGSGRVETVTLRQNELIRNLRVLVAVRFEQAISRIILVFAGQVLSDEGTIDSRGIVSGVTVHVVC 76

Human    72 QPLEKMALKEAHQPQTQPL---------------WHQLGLVLAKHFEPQDAKAVLQLLRQEHEER 121
            :      .:.|:.|...|:               |....:...:. ||...:::||.     :.|
  Fly    77 R------AEAANSPSPTPIAATKRSKPSERLMRSWQSAHIAFLQQ-EPDVLRSLLQA-----DPR 129

Human   122 LQKISLEHLEQLAQYL-----------LAEEPHVEPAGER 150
            ::.: |:....:..||           ||..|..:..|.|
  Fly   130 IRSL-LDENAAMRHYLNSDQNLREMLSLAFSPAKQELGRR 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UBL4B	NP_981957.1	UBQ	1..74	CDD:320785	16/66 (24%)
		FlhF	20..>154	CDD:332151	30/166 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..174		3/10 (30%)
CG31528	NP_730833.1	UBQ	7..77	CDD:294102	16/64 (25%)
CG31528	NP_730833.1	UBA_like_SF	299..335	CDD:304366
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900