Protein Alignment Hsd11b1 and CG31937

DIOPT Version :10

• Sequence 1: XP_006497291.1
• Gene: Hsd11b1 / 15483
• MGIID: 103562
• Length: 304
• Species: Mus musculus
• Sequence 2: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 248
• Identity: 67/248 - (27%)
• Similarity: 113/248 - (45%)
• Gaps: 33/248 - (13%)

Mouse    19 YLLPILVLFLAYY-------------YYSTNEEFRPEMLQGKKVIVTGASKGIGREMAYHLSKMG 70
            :||.:|||:...|             :|.:........::|:.|.:||||.||||.:|..|::.|
  Fly     6 FLLLLLVLYYVVYVLLWILLDCNVALWYKSRFGVSLSSMRGQVVWITGASSGIGRALALSLARHG 70

Mouse    71 AHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTME------DMTFAEQFIVKAGKLMG---GLD 126
            ..:||:||..|.|::|...||    |:|..:..|.:      ||...::.......::.   .||
  Fly    71 VKLVLSARRLEQLEQVQEECL----AAARGLLATKDVLVIQMDMLDLDEHKTHLNTVLNHFHRLD 131

Mouse   127 MLILNHITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQSNGS---IAVISSLAGKMT 188
            :|:.|.......|....:|...|.:.|::..:.|.:|...:....:.||.   ||..||:||...
  Fly   132 VLVNNAGRSQRASWTEVEIEVDRELFELDVFAVVHLSRLVVRYFVEQNGGRGHIAATSSIAGFSP 196

Mouse   189 QPMIAPYSASKFALDGFFSTIRTELYITKVNVSITLCVLGLIDTETAMKEISG 241
            .|....|.|:|.||:.:..:::.|:  .|::||  |...|.|.|:...:..:|
  Fly   197 VPFSPTYCAAKHALNAYLLSLKVEM--RKLDVS--LFAPGPIATDFLQEAFTG 245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsd11b1	XP_006497291.1	11beta-HSD1_like_SDR_c	44..291	CDD:187593	60/210 (29%)
CG31937	NP_608616.2	Rossmann-fold NAD(P)(+)-binding proteins	44..293	CDD:473865	60/210 (29%)