DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hoxb9 and ey

DIOPT Version :9

Sequence 1:	NP_032296.2	Gene:	Hoxb9 / 15417	MGIID:	96190	Length:	250	Species:	Mus musculus
Sequence 2:	NP_001014693.1	Gene:	ey / 43812	FlyBaseID:	FBgn0005558	Length:	898	Species:	Drosophila melanogaster

Alignment Length:	260	Identity:	58/260 - (22%)
Similarity:	90/260 - (34%)	Gaps:	83/260 - (31%)

- Green bases have known domain annotations that are detailed below.

Mouse     5 GTLSSY------YVDSIISHESEDAPPAKFPSGQYANPRQPGHAEHLDFPSCSFQPKAPVFGASW 63
            ||.||:      ...::..|:.:..||..:....|     |.....:...|      ||    :.
  Fly   336 GTRSSHPQLVHGNHQALQQHQQQSWPPRHYSGSWY-----PTSLSEIPISS------AP----NI 385

Mouse    64 APLSPHASGSLPSVYHPYLQP------------QGAP-AAESRYLRTWLEPAPRAEAAPGQGQAA 115
            |.::.:|||  ||:.|....|            :..| |.|..:|:..|:.....|...|:|
  Fly   386 ASVTAYASG--PSLAHSLSPPNDIESLASIGHQRNCPVATEDIHLKKELDGHQSDETGSGEG--- 445

Mouse   116 VKAEPLLGAPGELLKQGTPEYSLETSAGREAVLSNQRAGYGDNKICEGSEDKERPDQTNPSANWL 180
                                   |.|.|..:.:.|             :||    ||    |..:
  Fly   446 -----------------------ENSNGGASNIGN-------------TED----DQ----ARLI 466

Mouse   181 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK 245
            ..|..::.|..:|..|...|||||....|.....|..:|..:.|.|.::::||.|||.|.::..|
  Fly   467 LKRKLQRNRTSFTNDQIDSLEKEFERTHYPDVFARERLAGKIGLPEARIQVWFSNRRAKWRREEK 531

Mouse 246 245
Fly 532 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb9	NP_032296.2	Hox9_act	1..172	CDD:398350	34/185 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..48		4/26 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	160..182		5/21 (24%)
		Homeobox	188..242	CDD:395001	19/53 (36%)
ey	NP_001014693.1	PAX	98..221	CDD:128645
ey	NP_001014693.1	Homeobox	475..527	CDD:278475	19/51 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910