DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hoxb9 and bcd

DIOPT Version :9

Sequence 1:	NP_032296.2	Gene:	Hoxb9 / 15417	MGIID:	96190	Length:	250	Species:	Mus musculus
Sequence 2:	NP_788587.1	Gene:	bcd / 40830	FlyBaseID:	FBgn0000166	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	175	Identity:	48/175 - (27%)
Similarity:	70/175 - (40%)	Gaps:	27/175 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse    78 YHPYLQPQGAPAAESRYLRTWLEPAPRAEAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSA 142
            :||.......|...|       .|.|.:...|......::..|....|.:||        .:...
  Fly    12 HHPLPHTHTHPHPHS-------HPHPHSHPHPHHQHPQLQLPPQFRNPFDLL--------FDERT 61

Mouse   143 GREAVLSNQRAGYGDNKICEGS--EDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFL 205
            |  |:..|....|..|::.:..  ..:|.||.       |..|..|:.|..:|..|..|||:.||
  Fly    62 G--AINYNYIRPYLPNQMPKPDVFPSEELPDS-------LVMRRPRRTRTTFTSSQIAELEQHFL 117

Mouse   206 FNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE 250
            ...|||..|..:::..|.|...||||||:||| :..|:..:|.|:
  Fly   118 QGRYLTAPRLADLSAKLALGTAQVKIWFKNRR-RRHKIQSDQHKD 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hoxb9	NP_032296.2	Hox9_act	1..172	CDD:398350	18/95 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	21..48
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	160..182		4/23 (17%)
		Homeobox	188..242	CDD:395001	23/53 (43%)
bcd	NP_788587.1	Homeobox	106..153	CDD:278475	21/47 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000007
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000