DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hgs and CG41099

DIOPT Version :8

Sequence 1:XP_006532333.2 Gene:Hgs / 15239 MGIID:104681 Length:805 Species:Mus musculus
Sequence 2:NP_001015359.1 Gene:CG41099 / 3355072 FlyBaseID:FBgn0039955 Length:1124 Species:Drosophila melanogaster

Alignment Length:337 Identity:74/338 (22%)
Similarity:110/338 (33%) Gaps:140/338 (41%)


Mouse     3 RGSGTFERLLDK---ATSQL-----------LLETDWESILQICDLIRQGDTQAKYAVNSIKKKV 53
            |.....:|:||:   |..|:           :|:.|.||:|.:  |..|.|      |||.....
  Fly   800 RNHNAAQRILDRFPTAAEQMDIRGRNFLHLAILKDDLESVLFL--LAIQVD------VNSRVHDA 856

Mouse    54 NDKNP----------------------------------HVALYA--LEVMESVVKN-------- 74
            |..:|                                  |:|:..  |..:.::::|        
  Fly   857 NQSSPLHLAAASQNEMITRNLILAGARMNERDAVQKLPLHIAIERGNLPAVSALIQNNADYDATD 921

Mouse    75 ------------CGQ-----------TVHDEVANKQTMEELKELLKRQVEVNVRNKILYLIQAWA 116
                        |.|           .|:.|..|.:....|.||. |.||.:....|..|.    
  Fly   922 ADGNNALHIAVRCAQFFIVRELLTESRVNAEATNLKGRNPLHELC-RVVEDSTAGLICELF---- 981

Mouse   117 HAFRNEPKYKVVQDTYQIMKVEGH------------------------VFPEFKESDAMFAAERA 157
              ..:.|||.:     .|..::|:                        :..|.|:...:|..:.|
  Fly   982 --LESMPKYPI-----NIPDMDGNTPLLLSFMRGQSPLCKILVKAGACLGTENKDGINIFNFKLA 1039

Mouse   158 PD---------------WVDAEECHRCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEK 207
            .|               |.:::.|..|..:|.:..||||||.||::.|.|||.....|.||||.|
  Fly  1040 TDQLLHNLLDQLPQESPWAESDYCQHCTNRFTITMRKHHCRHCGRVLCSKCSCNDVPILKFGINK 1104

Mouse   208 EVRVCEPCYEQL 219
            .||||..|:..|
  Fly  1105 PVRVCTVCFNVL 1116

Known Domains:


GeneSequenceDomainRegion External IDIdentity
HgsXP_006532333.2 VHS_Hrs_Vps27p 4..145 CDD:239626 41/246 (17%)
FYVE_Hrs 159..219 CDD:277260 28/75 (37%)
BASP1 220..397 CDD:283191 74/338 (22%)
Hrs_helical 413..507 CDD:289018
GBP_C <492..566 CDD:303769
DUF1421 525..>769 CDD:284607
coiled coil 537..548 CDD:293879
CG41099NP_001015359.1 BTB 67..164 CDD:279045
BTB 75..166 CDD:197585
ANK 252..385 CDD:238125
ANK repeat 291..322 CDD:293786
ANK repeat 325..362 CDD:293786
Ank_2 330..431 CDD:289560
ANK 463..595 CDD:238125
ANK repeat 468..501 CDD:293786
Ank_2 473..572 CDD:289560
ANK repeat 503..539 CDD:293786
ANK 536..660 CDD:238125
ANK repeat 541..572 CDD:293786
ANK repeat 574..637 CDD:293786
Ank_2 579..670 CDD:289560
ANK repeat 639..670 CDD:293786
Ank_2 644..752 CDD:289560
ANK repeat 672..721 CDD:293786
ANK 721..843 CDD:238125 11/45 (24%)
ANK repeat 723..752 CDD:293786
ANKYR 752..977 CDD:223738 34/186 (18%)
ANK repeat 754..786 CDD:293786
ANK 820..944 CDD:238125 19/132 (14%)
ANK repeat 822..855 CDD:293786 11/41 (27%)
ANK repeat 857..888 CDD:293786 2/31 (6%)
ANK 885..1017 CDD:238125 22/144 (15%)
ANK repeat 890..921 CDD:293786 4/31 (13%)
ANK repeat 923..955 CDD:293786 4/32 (13%)
ANK repeat 996..1021 CDD:293786 1/25 (4%)
FYVE_ANFY1 1054..1116 CDD:277267 27/62 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG1818
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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