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Protein Alignment CTSV and CtsF

DIOPT Version :9

Sequence 1:	NP_001324.2	Gene:	CTSV / 1515	HGNCID:	2538	Length:	334	Species:	Homo sapiens
Sequence 2:	NP_730901.1	Gene:	CtsF / 40628	FlyBaseID:	FBgn0260462	Length:	614	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	125/320 - (39%)
Similarity:	181/320 - (56%)	Gaps:	19/320 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    20 KFDQNLDTKWYQWKATH-RRLYGANEEGWRRAVWEKNMKMI-ELHNGEYSQGKHGFTMAMNAFGD 82
            :||: :|..:|:::... ||.....|...|..::.:|:|.| ||:..|....|:|.|    .|.|
  Fly   300 RFDK-VDHLFYKFQVRFGRRYVSTAERQMRLRIFRQNLKTIEELNANEMGSAKYGIT----EFAD 359

Human    83 MTNEEFRQMMGCFRNQ--KFRKGKVFREPLFL-DLPKSVDWRKKGYVTPVKNQKQCGSCWAFSAT 144
            ||:.|:::..|.::..  |...|.....|.:. :|||..|||:|..||.||||..||||||||.|
  Fly   360 MTSSEYKERTGLWQRDEAKATGGSAAVVPAYHGELPKEFDWRQKDAVTQVKNQGSCGSCWAFSVT 424

Human   145 GALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDE 209
            |.:||....|||:|...|||.|:||...  :..||||.|..|::.:|:.|||:.|..|||.|...
  Fly   425 GNIEGLYAVKTGELKEFSEQELLDCDTT--DSACNGGLMDNAYKAIKDIGGLEYEAEYPYKAKKN 487

Human   210 ICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIY--FEPDCSS 272
            .|.:....|.....||..:..|.|.|:.:.:...||||:.::|  ::.|||:.|:.  ::..||.
  Fly   488 QCHFNRTLSHVQVAGFVDLPKGNETAMQEWLLANGPISIGINA--NAMQFYRGGVSHPWKALCSK 550

Human   273 KNLDHGVLVVGYGF-EGANSNNS-KYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAAS 330
            |||||||||||||. :..|.:.: .||:|||||||.||..||.::.:. :|.||::..|:
  Fly   551 KNLDHGVLVVGYGVSDYPNFHKTLPYWIVKNSWGPRWGEQGYYRVYRG-DNTCGVSEMAT 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CTSV	NP_001324.2	Inhibitor_I29	29..87	CDD:214853	18/59 (31%)
CTSV	NP_001324.2	Peptidase_C1	114..332	CDD:425470	99/221 (45%)
CtsF	NP_730901.1	Inhibitor_I29	308..365	CDD:462410	18/60 (30%)
CtsF	NP_730901.1	Peptidase_C1A	395..611	CDD:239068	98/220 (45%)

Information from Original Tools:

Software error:

Can't use an undefined value as an ARRAY reference at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 1034.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.