Protein Alignment CTSV and CtsL1

DIOPT Version :10

• Sequence 1: NP_001324.2
• Gene: CTSV / 1515
• HGNCID: 2538
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_523735.2
• Gene: CtsL1 / 36546
• FlyBaseID: FBgn0013770
• Length: 371
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 171/333 - (51%)
• Similarity: 225/333 - (67%)
• Gaps: 14/333 - (4%)

Human    12 LGIASAVPKFDQNLDTKWYQWKATHRRLY-GANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTM 75
            |.:|.||...|..:: :|:.:|..||:.| ...||.:|..::.:|...|..||..:::||..|.:
  Fly    43 LAVAQAVSFADVVME-EWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKL 106

Human    76 AMNAFGDMTNEEFRQMMGCFR---NQKFR------KGKVFREPLFLDLPKSVDWRKKGYVTPVKN 131
            |:|.:.|:.:.||||:|..|.   :::.|      ||..|..|..:.||||||||.||.||.||:
  Fly   107 AVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKD 171

Human   132 QKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGL 196
            |..||||||||:|||||||.|||:|.|||||||||||||...||.|||||.|..||:|:|:|||:
  Fly   172 QGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGI 236

Human   197 DSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYK 261
            |:|:||||.|:|:.|.:......|.|.|||.:..|.||.:.:|||||||:|||:||.|.|||||.
  Fly   237 DTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYS 301

Human   262 SGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIA 326
            .|:|.||.|.::||||||||||:   |.:.:...|||||||||..||..|::|:.::|.|.||||
  Fly   302 EGVYNEPQCDAQNLDHGVLVVGF---GTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIA 363

Human   327 TAASYPNV 334
            :|:|||.|
  Fly   364 SASSYPLV 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSV	NP_001324.2	Inhibitor_I29	29..87	CDD:214853	18/58 (31%)
		Peptidase_C1	114..332	CDD:425470	134/217 (62%)
CtsL1	NP_523735.2	Inhibitor_I29	59..118	CDD:214853	18/58 (31%)
		Peptidase_C1	154..370	CDD:425470	135/218 (62%)