Protein Alignment CTSV and CG6347

DIOPT Version :9

• Sequence 1: NP_001188504.1
• Gene: CTSV / 1515
• HGNCID: 2538
• Length: 334
• Species: Homo sapiens
• Sequence 2: NP_610906.1
• Gene: CG6347 / 36531
• FlyBaseID: FBgn0033874
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 350
• Identity: 125/350 - (35%)
• Similarity: 189/350 - (54%)
• Gaps: 28/350 - (8%)

Human     1 MNLSL-VLAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELH 62
            |.|.| :|.|..|....:.||.  .||.|    .:.....::|...|..:|.:::...|.:|.|.
  Fly    11 MTLGLALLGAVSLQQLQSFPKLCDVQNFD----DFLRQTGKVYSDEERVYRESIFAAKMSLITLS 71

Human    63 NGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGC----FRNQKFRKGKV----FREPLFLDLPKSVD 119
            |.....|..||.:.:|...|||.:|...::|.    | .:::..|.:    .|.|...:||:..|
  Fly    72 NKNADNGVSGFRLGVNTLADMTRKEIATLLGSKISEF-GERYTNGHINFVTARNPASANLPEMFD 135

Human   120 WRKKGYVTPVKNQ-KQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFM 183
            ||:||.|||...| ..||:||:|:.||||||.:||:||.|.|||:||||||:...||.||:|||.
  Fly   136 WREKGGVTPPGFQGVGCGACWSFATTGALEGHLFRRTGVLASLSQQNLVDCADDYGNMGCDGGFQ 200

Human   184 ARAFQYVKENGGLDSEESYPYVAVDEICKYR------PENSVANDTGFTVVAPGKEKALMKAVAT 242
            ...|:|:::: |:.....|||...:..|:..      |..|:.....:..:.||.|:.:.:.:||
  Fly   201 EYGFEYIRDH-GVTLANKYPYTQTEMQCRQNETAGRPPRESLVKIRDYATITPGDEEKMKEVIAT 264

Human   243 VGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEW 307
            :||::.:|:|...||:.|..|||.:.:|:...|:|.|.|||||.|    |...||::|||:...|
  Fly   265 LGPLACSMNADTISFEQYSGGIYEDEECNQGELNHSVTVVGYGTE----NGRDYWIIKNSYSQNW 325

Human   308 GSNGYVKIAKDKNNHCGIATAASYP 332
            |..|:::|.::....||||:..|||
  Fly   326 GEGGFMRILRNAGGFCGIASECSYP 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CTSV	NP_001188504.1	Inhibitor_I29	29..87	CDD:214853	14/57 (25%)
		Peptidase_C1	114..332	CDD:306594	92/224 (41%)
CG6347	NP_610906.1	Inhibitor_I29	38..97	CDD:285458	15/62 (24%)
		Peptidase_C1A	131..350	CDD:239068	91/223 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149670
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	1	1.010	-	-		D1275401at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.860