DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CTSV and CG5367

Sequence 1:NP_001188504.1 Gene:CTSV HGNCID:2538 Length:334 Species:Homo sapiens
Sequence 2:NP_609387.1 Gene:CG5367 FlyBaseID:FBgn0032228 Length:338 Species:Drosophila melanogaster

Alignment Length:337 Identity:120/338 (36%)
Similarity:196/338 (58%) Gaps:20/338 (6%)


Human     1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRR-AVWEKNMKMIELHNG 64
            :|..:|.:....|.:|:.     |..:::.::|..:.|.|....:..|. ..:|:|.|:||.||.
  Fly    13 LNCQIVTSNLSEGNSSSA-----NCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQ 72

Human    65 EYSQGKHGFTMAMNAFGDMTNEEF-----RQMMGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG 124
            .|.:|:..|.:..|.|.||:.:.:     |.:.....:......::...||..::|:|:|||.||
  Fly    73 NYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKG 137

Human   125 YVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQY 189
            ::||..||..||||:|||...::.||:|::|||::|||:|.:||||...|||||.||.:.....|
  Fly   138 FITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSY 202

Human   190 VKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGH 254
            ::..||:..::.|||||....|::.|:.||.|.|.:.::....|:|:..||..:||::::::|..
  Fly   203 LQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASP 267

Human   255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDK 319
            .:||.|..|||.:|.|||.:::|.::|:|:|        ..||::||.||..||.|||::|.|..
  Fly   268 KTFQLYSDGIYDDPLCSSASVNHAMVVIGFG--------KDYWILKNWWGQNWGENGYIRIRKGV 324

Human   320 NNHCGIATAASY 331
             |.||||..|:|
  Fly   325 -NMCGIANYAAY 335

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CTSVNP_001188504.1 Inhibitor_I29 29..87 CDD:214853 18/59 (31%)
Peptidase_C1 114..332 CDD:306594 94/219 (43%)
CG5367NP_609387.1 Inhibitor_I29 36..96 CDD:285458 18/60 (30%)
Peptidase_C1A 128..336 CDD:239068 94/218 (43%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 C87870935
eggNOG 1 0.900 E1_COG4870
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 0 Normalized mean entropy S2922
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D1275401at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.790

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