DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gria1 and Ir94d

DIOPT Version :10

Sequence 1:NP_032191.2 Gene:Gria1 / 14799 MGIID:95808 Length:907 Species:Mus musculus
Sequence 2:NP_001138099.1 Gene:Ir94d / 7354412 FlyBaseID:FBgn0259193 Length:593 Species:Drosophila melanogaster


Alignment Length:440 Identity:78/440 - (17%)
Similarity:140/440 - (31%) Gaps:152/440 - (34%)


- Green bases have known domain annotations that are detailed below.


Mouse   466 ARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPG--- 527
            |||......||.| ::..|    |:.|      :.....:|.|...:...:|:..|::....   
  Fly   239 ARDLIASVQNGSV-QIALG----AIYP------QVPYTGYSYPIELMSWCLMMPVPEEVPHSQLY 292

Mouse   528 --VFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSR-------FSPYEWHSEEFEEGRDQTTSDQSN 583
              |||   |:|:.|   .:.|.:.:|:.|.:..|       ||.|..|.....            
  Fly   293 SMVFS---PMAFGI---TIVAMVLISLTLSMALRLHGYRVSFSEYFLHDSCLR------------ 339

Mouse   584 EFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIE 648
              |:.:..::.:   ::....|....|...::|       |:|.|.|.:..:.|:|.......:.
  Fly   340 --GVLSQSFYEV---LRAPALIKAMYLVICLLG-------LLITSWYNSYFSTFVTSAPRFPQLT 392

Mouse   649 SAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGK 713
            |.|.:                    |.|.|.:.  :|            :...|.::...::..|
  Fly   393 SYESI--------------------RHSNIKIV--IW------------KPEYEMLLFFSENMEK 423

Mouse   714 YA--YLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATP------------------------- 751
            |:  :.|:....|::..|...||.          ||...|                         
  Fly   424 YSSIFQLQEDYKEFLHLRDSFDTR----------YGYMMPMEKWSLMKEQQRVFSSPLFSLQDDL 478

Mouse   752 -------------KGSALRNPVNLAVLKLNEQGLLDKLKNKWWYD--------KGECGSGGGDSK 795
                         |.|..:.|.:..:|.:...|||.:     |.|        .|:.|.......
  Fly   479 CVFHTVPIVFPMVKNSIFKEPFDRLILDVTATGLLSR-----WRDMSFTEMIKAGQLGLEDRGHP 538

Mouse   796 DKTSALSLSNVAGVFYILIGGLGLAMLVALIE-FCYKSRSESKRMK-GFC 843
            .:..|:.:.::..::..:...||||.:|.|:| .|:......:.|| .||
  Fly   539 KEFRAMKVGDLIQIWRFVGWMLGLATIVFLLELICFWRHKMWQNMKYMFC 588

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gria1NP_032191.2 PBP1_iGluR_AMPA_GluR1 26..392 CDD:380613
PBP2_iGluR_AMPA_GluR1 406..787 CDD:270447 64/380 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 857..881
PDZ-binding 904..907
Ir94dNP_001138099.1 None
Blue background indicates that the domain is not in the aligned region.

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