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Protein Alignment Gria1 and CG11155

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster

Alignment Length:	841	Identity:	335/841 - (39%)
Similarity:	485/841 - (57%)	Gaps:	52/841 - (6%)

- Green bases have known domain annotations that are detailed below.

Mouse    16 VVGANFPNNIQIGGLF--PNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTY 72
            |:....|..|::|.:|  ..::|...:||::|:.::.:...|||      .|:.|...|||..|.
  Fly    34 VISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTK 98

Mouse    73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVD-TSNQFVLQLRPE---LQEAL 133
            :.|||...||.||||..:....:.:.|.|.|..:..|.....:: .|.:|.:.|.|.   |..|.
  Fly    99 KVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLYPSHTLLTLAY 163

Mouse   134 ISIIDHYKWQTFVYIYDADRGL-SVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKE 197
            ..|:.:..|.....||:.|.|| :::....:|.||       :.|...:.:.||.:.:.:.:|:.
  Fly   164 RDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAE-------MYIRQASPDSYRQVLRAIRQKEI 221

Mouse   198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTI 262
            ..::||.....:.:....|::|:.|...|||:.........||..|:.:..|:|.|:||   |..
  Fly   222 YKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLV---DVD 283

Mouse   263 PARIMQQWRTSDARDHTRVDWKRP----KYTSALTYDGVKVMAEAFQSL---RRQRIDISRRGNA 320
            ..|.::.........|..:|....    :..|||.:|.|...|.....|   ..|...|......
  Fly   284 SKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCT 348

Mouse   321 GDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNED 385
            .|      ..|..||.:...:.....:||||.|||.| |||..:.|.::::|.:.|:|:|||:.|
  Fly   349 SD------QTWNDGISLYNQINAAITDGLTGTVQFVE-GRRNIFKLDILKLKQEKIQKVGYWHPD 406

Mouse   386 DKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHV 450
            |..  ..:|..|..| |::.|.|.:|.|..|.||||:|::.| ..||.|:||:|::|...||..|
  Fly   407 DGV--NISDPTAFYD-SNIANITLVVMTREERPYVMVKEDKN-LTGNLRFEGFCIDLLKAIATQV 467

Mouse   451 GYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515
            |:.|::|:|.|..||...|:|.:|||:|.||:..|||:|||.:||...||.||||:||||:|||.
  Fly   468 GFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIG 532

Mouse   516 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEE--FEEGRDQTT 578
            |:.|.|......:|||::|||.|||:.::.|||.||..||:::|||||||.:..  ::|     |
  Fly   533 ILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKE-----T 592

Mouse   579 SDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERM 643
            ....|:|.|.||.||..|.|::||..::|::.|.|||||.|:||.||||||||||||||||||||
  Fly   593 DIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERM 657

Mouse   644 VSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVR 708
            :||||||.|||:||||:|||||.|||..|||.|||.:::|||.||::.:.:|||:|.|:|:.||
  Fly   658 ISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRV- 721

Mouse   709 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVL 773
             .:|.||:|:||||.:|..|| .|:..::||.||||||||||||||..|..::||:|:|.|:|::
  Fly   722 -MEGSYAFLMESTMLDYAVQR-DCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGII 784

Mouse   774 DKLKSKWWYDKGE-CGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSR 833
            ..|..|||.:.|: |...|...:.|.:||.:.|:.|||.:|:.||.||::||:.|||:.||
  Fly   785 QILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSR 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.