Protein Alignment: Gria1 and CG11155

• Sequence 1: NP_001106796.1
• Gene: Gria1
• MGIID: 95808
• Length: 907
• Species: Mus musculus
• Sequence 2: NP_651941.2
• Gene: CG11155
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Alignment Length: 841
• Identity: 335/842 (40%)
• Similarity: 485/842 (58%)
• Gaps: 52/842 (6%)

Mouse    16 VVGANFPNNIQIGGLF--PNQQSQEHAAFRFALSQLTEPPKLLP------QIDIVNISDSFEMTY 72
            |:....|..|::|.:|  ..::|...:||::|:.::.:...|||      .|:.|...|||..|.
  Fly    34 VISNALPPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPRDDSFRTTK 98

Mouse    73 RFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVD-TSNQFVLQLRPE---LQEAL 133
            :.|||...||.||||..:....:.:.|.|.|..:..|.....:: .|.:|.:.|.|.   |..|.
  Fly    99 KVCSQLEAGVQAIFGPTDALLASHVQSICEAYDIPHIEGRIDLEYNSKEFSINLYPSHTLLTLAY 163

Mouse   134 ISIIDHYKWQTFVYIYDADRGL-SVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKE 197
            ..|:.:..|.....||:.|.|| :::....:|.||       :.|...:.:.||.:.:.:.:|:.
  Fly   164 RDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAE-------MYIRQASPDSYRQVLRAIRQKEI 221

Mouse   198 RLVVVDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTI 262
            ..::||.....:.:....|::|:.|...|||:.........||..|:.:..|:|.|:||   |..
  Fly   222 YKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMFTTFDLETYDLEDFRYNSVNITAFRLV---DVD 283

Mouse   263 PARIMQQWRTSDARDHTRVDWKRP----KYTSALTYDGVKVMAEAFQSL---RRQRIDISRRGNA 320
            ..|.::.........|..:|....    :..|||.:|.|...|.....|   ..|...|......
  Fly   284 SKRYLEVINQMQKLQHNGLDTINGSPYIQTESALMFDSVYAFANGLHFLNLDNHQNFYIKNLSCT 348

Mouse   321 GDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNED 385
            .|      ..|..||.:...:.....:||||.|||.| |||..:.|.::::|.:.|:|:|||:.|
  Fly   349 SD------QTWNDGISLYNQINAAITDGLTGTVQFVE-GRRNIFKLDILKLKQEKIQKVGYWHPD 406

Mouse   386 DKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHV 450
            |..  ..:|..|..| |::.|.|.:|.|..|.||||:|::.| ..||.|:||:|::|...||..|
  Fly   407 DGV--NISDPTAFYD-SNIANITLVVMTREERPYVMVKEDKN-LTGNLRFEGFCIDLLKAIATQV 467

Mouse   451 GYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGIS 515
            |:.|::|:|.|..||...|:|.:|||:|.||:..|||:|||.:||...||.||||:||||:|||.
  Fly   468 GFQYKIELVPDNMYGVYIPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIG 532

Mouse   516 IMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHSEE--FEEGRDQTT 578
            |:.|.|......:|||::|||.|||:.::.|||.||..||:::|||||||.:..  ::|     |
  Fly   533 ILFKVPTSQPTRLFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKE-----T 592

Mouse   579 SDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERM 643
            ....|:|.|.||.||..|.|::||..::|::.|.|||||.|:||.||||||||||||||||||||
  Fly   593 DIVENQFSISNSFWFITGTFLRQGSGLNPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVERM 657

Mouse   644 VSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVR 708
            :||||||.|||:||||:|||||.|||..|||.|||.:::|||.||::.:.:|||:|.|:|:.||
  Fly   658 ISPIESASDLAEQTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRV- 721

Mouse   709 KSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVL 773
             .:|.||:|:||||.:|..|| .|:..::||.||||||||||||||..|..::||:|:|.|:|::
  Fly   722 -MEGSYAFLMESTMLDYAVQR-DCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGII 784

Mouse   774 DKLKSKWWYDKGE-CGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSR 833
            ..|..|||.:.|: |...|...:.|.:||.:.|:.|||.:|:.||.||::||:.|||:.||
  Fly   785 QILYDKWWKNTGDVCNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSR 845

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gria1	NP_001106796.1	PBP1_iGluR_AMPA_GluR1	26..389	CDD:107385	101/383 (26%)
		ANF_receptor	37..372	CDD:279440	90/353 (25%)
		PBP2_iGluR_AMPA_GluR1	406..787	CDD:270447	206/384 (54%)
		Glutamate binding. {ECO:0000250}	492..494		0/2 (0%)
		Lig_chan	538..817	CDD:278489	151/282 (54%)
		Glutamate binding. {ECO:0000250}	668..669		1/1 (100%)
		PDZ-binding	904..907
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	101/385 (26%)
		ANF_receptor	61..393	CDD:279440	90/349 (26%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	205/378 (54%)
		Lig_chan	555..829	CDD:278489	151/282 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C110989546
eggNOG	1	0.900				E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830