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Protein Alignment Gria1 and Ekar

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_001036250.1	Gene:	Ekar / 43806	FlyBaseID:	FBgn0039916	Length:	899	Species:	Drosophila melanogaster

Alignment Length:	886	Identity:	320/886 - (36%)
Similarity:	488/886 - (55%)	Gaps:	84/886 - (9%)

- Green bases have known domain annotations that are detailed below.

Mouse    18 GANFPNNIQIGGLFPNQQSQEHA--AFRFALSQLTEPPKLLPQ------IDIVNISDSFEMTYRF 74
            |...|..::||.:|.||....::  |||:|:.:|.....|||:      ::.||..||||...:.
  Fly    16 GLGVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKV 80

Mouse    75 CSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFVLQLRPELQ---EALISI 136
            |.....||.|:|...:......:.|.|.||.:..|..|     ::.|.:.:.|..|   .|...:
  Fly    81 CKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRS-----AHDFSINVYPSKQLVNYAFNDV 140

Mouse   137 IDHYKWQTFVYIYDADRGLSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVV 201
            |.:..|..|..:::.:.|:..|.::..:...:      |::...:.:.|.....:.:.|:...::
  Fly   141 IQYLNWTRFGILHEKENGIINLHQLSRSFHGE------VHMRQVSRDSYVSALNEFKGKEIHNII 199

Mouse   202 VDCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARI 266
            :|..|..::.:|..|::.:.|...|||:..:......||..||.:..|:|.|:||:..|....:|
  Fly   200 IDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQI 264

Mouse   267 MQQWRTSDARDHTRVDWKRP-------KYT-----SALTYDGVKVMAEAFQSLRRQR----IDIS 315
            ::     |...::...:|:|       |.|     .||.:|.|.|.|...|:|.:..    ::||
  Fly   265 LK-----DIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNIS 324

Mouse   316 RRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIG 380
                   |....:  |..|:.:...|..|.::||||.:||.: |:|..:.|.:|::|...|.|:|
  Fly   325 -------CEEENS--WDGGLSLINYLNAVEWKGLTGPIQFKD-GQRVQFKLDLIKLKQHSIVKVG 379

Mouse   381 YW--------NEDDKFVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEG 437
            .|        .|...|..|.:           .|.|.:|.||||.||||:....| |.||:|:.|
  Fly   380 EWTPHGHLNITEPSMFFDAGS-----------MNVTLVVITILETPYVMMHYGKN-FTGNERFYG 432

Mouse   438 YCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEV 502
            :||::...|::.||:.|.|::|.|.||||:||:|..|||||.:|:..:||:||..:|||..||.|
  Fly   433 FCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESV 497

Mouse   503 IDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHS 567
            |||:||||:|||||:.|.|......:|||::|||.|||:.::.||..||:.:::|.:.||.||
  Fly   498 IDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEW-- 560

Mouse   568 EEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 632
             :.....|.......|:|.:.:|.||::|.||||..||.||::|.||:...|.||:|||::||||
  Fly   561 -KCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTA 624

Mouse   633 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFV 697
            |||||||.|||::|||:|||||.||||:||||::|||..|||.|.|..::|:|..|.:.:||.|.
  Fly   625 NLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFT 689

Mouse   698 RTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNL 762
            .|.|:|:.||  ::|.||:|:||||.:||.|| .|:..::||.||:|||||||||||..|..::|
  Fly   690 TTYEDGIKRV--NQGNYAFLMESTMLDYIVQR-DCNLTQIGGLLDTKGYGIATPKGSPWRDKISL 751

Mouse   763 AVLKLSEQGVLDKLKSKWWYDKGE-CGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALI 826
            |:|:|.|:|.:..|..|||.:..| |..|::..:.|.::|.|.::.|||.:||.|:.:|.:||..
  Fly   752 AILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFF 816

Mouse   827 EFCYKSRSESKRMKGFCLI----PQQSINEAIRTSTLPRNS 863
            ||.|..|...:......::    .|..|.|:.|..|.|..|
  Fly   817 EFWYNFRYNYEATPSQSVVNNKYNQDGILESERNYTPPDRS 857

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.