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Protein Alignment Gria1 and Ir68a

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_648455.2	Gene:	Ir68a / 39269	FlyBaseID:	FBgn0036150	Length:	704	Species:	Drosophila melanogaster

Alignment Length:	822	Identity:	151/822 - (18%)
Similarity:	284/822 - (34%)	Gaps:	254/822 - (30%)

- Green bases have known domain annotations that are detailed below.

Mouse   104 LHVCFIT----PSFPVDTSNQ-----FVLQLRPELQEALISIIDHYKW-----QTFVYIYDADRG 154
            |.|.||:    .|.|:..:|.     :.:||:..||:.|        |     :.|..|.| |..
  Fly     7 LIVAFISLAMATSIPIPIANPAPLSGYEMQLKILLQKIL--------WVANVKRCFAVITD-DLH 62

Mouse   155 LSVLQRVLDTAAEKNWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVV-------DCESERLNAI 212
            ..:..|:...:..:  :|....::.|.|.      .||::...::.:.       |||...:..:
  Fly    63 YPIYDRIFFESVGR--RVIPFFVMRTNES------DDLQRPSRQVELFVKAIKSSDCELNVITIL 119

Mouse   213 LG-QIVKLEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQQWRT-SDA 275
            .| |:.:.    :||.|       .:..||..|:       |.|::......:.::..|.. .||
  Fly   120 NGWQVQRF----LGYIY-------DNRSLNMQKK-------FVLLHDLRLFESDMIHLWSVFIDA 166

Mouse   276 RDHTRVDWKRP---KYT-SALTY----DGVKVMAEAFQSLRRQRIDISRRGNAGDCLANPAVPWG 332
                 :..||.   ||| |.:.:    .||.||..                     :||    |.
  Fly   167 -----IFLKRQLDNKYTISTIAFPGILSGVLVMKN---------------------IAN----WE 201

Mouse   333 QGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQA 397
            .|            :||.|.:.|
  Fly   202 LG------------KGLNGRILF------------------------------------------ 212

Mouse   398 GGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYEGYCVELAAEIAKHVGYS---YR---- 455
             .|.:|....|.:...|.|...::|..||.:     .::|..||:...:.|.:.:.   |:
  Fly   213 -ADKTSNLFGTSLPVAISEHVPMVLWANATK-----SFQGVEVEIMNALGKALNFKPVYYKPNQT 271

Mouse   456 -------LEIVSDGKYGARDPDTKAWNG------MVGELVYGRADVAVAPLTITLVREEVIDFSK 507
                   |:..:...||:.:||..|.||      :|.|:....|..|:..|.:..|..::::.|.
  Fly   272 ENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSA 336

Mouse   508 PFMSLGISIMIKKPQKSKPGVF-SFLDPLAYEIWMCIVFAYIGVSVVLFLVS------------- 558
            |.....::.:  .|:.|....: :|:.|.:..:|:.::.:...|..|.:.:|
  Fly   337 PHNFECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSE 399

Mouse   559 -----------RFSPYEWHSEEFEEGRDQTTSDQSNEF------GIFNSLWFSLGAFMQQGCDIS 606
                       ...|..:....|.....:..|.:.:..      |..|.:..:....:.......
  Fly   400 FFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRM 464

Mouse   607 PRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGST-- 669
            ||:...|::.|.:|.:.::::::|.|:..|.|........|::.|||.: :.|...|   |:|
  Fly   465 PRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-SHIPPST---GATEN 525

Mouse   670 KEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLESTMNEYIEQRKPCDT 734
            ::||..:...|..|:...|:     ||..:.:   :..|.:||:.||........|:..
  Fly   526 RQFFLEANDEVARKVGEKME-----VFGYSDD---LTSRIAKGQCAYYDNEFYLRYLRV------ 576

Mouse   735 MKVGGNLDSKGYG--------------IATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKG 785
                  .|..|..              :|..|.|||:..|:.::..|:|.|::    :||..|..
  Fly   577 ------ADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGGLI----AKWLKDAI 631

Mouse   786 ECGSKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIE 827
            |....::.::.: :.:::......|..|:.|..::||..|.|
  Fly   632 EHLPAEALAQQE-ALMNIQKFWSSFVALLIGYVISMLTLLAE 672

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.