Protein Alignment: Gria1 and Ir64a

• Sequence 1: NP_001106796.1
• Gene: Gria1
• MGIID: 95808
• Length: 907
• Species: Mus musculus
• Sequence 2: NP_647962.1
• Gene: Ir64a
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 645
• Identity: 116/646 (18%)
• Similarity: 215/646 (33%)
• Gaps: 206/646 (32%)

Mouse   326 NPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVP 390
            ||.:.:|..:::.........||    :|.:...|.|:.....::|:|..:|          .:.
  Fly   266 NPGLNYGGHVNLTEIGSFTPTEG----IQLHTWFRTTSTVRRRMDMQHARVR----------CMV 316

Mouse   391 AATDAQAGGDNSSVQNRT-----YIVTTILEDPYVMLKKNANQFEG-NDRYEGYCVELAAEIAKH 449
            ..|:          :|.|     |:..|:......|.:.|.|.... .|.:....|     :::.
  Fly   317 VVTN----------KNMTGTLMYYLTHTMSGHIDTMNRFNFNLLMAVRDMFNWTFV-----LSRT 366

Mouse   450 VGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYGRADVAVAPLTITLVREEVIDFSKPFMSLGI 514
            ..:.|    |.:|::          :||:|.|:....|:..||:...|.|.:.||.:....|...
  Fly   367 TSWGY----VKNGRF----------DGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRP 417

Mouse   515 SIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVV-LFLVSRFSPYEWH------------ 566
            ..:.:.|:.::.....||.|...::|:.||    |..|: :|::...:..||.
  Fly   418 CFIFRHPRSTQKDRIVFLQPFTNDVWILIV----GCGVLTVFILWFLTTIEWKLVPHDGSALIKP 478

Mouse   567 --------------------------------------SEEFEEGRDQTTSD----------QSN 583
                                                  .|:.||..|.|..|          :.|
  Fly   479 KGGAPPRHHYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLN 543

Mouse   584 EF---------------GIF-NSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTA 632
            ::               |:| .|:.|.:|...|||...|...:|||.:......|:..|...|:|
  Fly   544 KYIKDRKAKQKKAPERVGLFLESVLFFVGIICQQGLGFSTSFVSGRCIVITSLLFSFCIYQFYSA 608

Mouse   633 NLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAGS-----TKEFFRRSKIAVFEKMWTYMK--- 689
            ::...|.:|: ...|::..||      .:.:|:.|.     .:::|..:|..|  .|..|.|
  Fly   609 SIVGTLLMEK-PKTIKTLSDL------VHSSLKVGMEDILYNRDYFLHTKDPV--SMELYAKKIT 664

Mouse   690 ---------------------SAEPSVFVR---------------------TTEEGMIRVRKSKG 712
                                 |.:|:...|                     ..|.|::|   ..|
  Fly   665 SVPTTKENEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLR---HLG 726

Mouse   713 KYAYLLE-----STMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772
             :|:.::     ..:.|...::..||..:|......|...| ..|.|.:|..::..:.:::|.|:
  Fly   727 -FAFHVDVAAAYKIIAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGI 789

Mouse   773 LDKLKSKWWYDKGECGSKDSGSKDKTSAL--SLSNVAGVFYILIGGLGLAMLVALIEFCY 830
            |....:.|...|..|     ..|.:||.|  .:..|:....||:....:.:::...|..|
  Fly   790 LTYHFNVWHSRKPPC-----VKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILY 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gria1	NP_001106796.1	PBP1_iGluR_AMPA_GluR1	26..389	CDD:107385	11/63 (17%)
		ANF_receptor	37..372	CDD:279440	9/46 (20%)
		PBP2_iGluR_AMPA_GluR1	406..787	CDD:270447	94/519 (18%)
		Glutamate binding. {ECO:0000250}	492..494		1/2 (50%)
		Lig_chan	538..817	CDD:278489	74/413 (18%)
		Glutamate binding. {ECO:0000250}	668..669		0/6 (0%)
		PDZ-binding	904..907
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:304360	28/137 (20%)
		Lig_chan	563..828	CDD:278489	58/284 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C111361140
eggNOG	1	0.900				E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930