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Protein Alignment Gria1 and Ir31a

DIOPT Version :9

Sequence 1:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus
Sequence 2:	NP_001260346.1	Gene:	Ir31a / 318912	FlyBaseID:	FBgn0051718	Length:	648	Species:	Drosophila melanogaster

Alignment Length:	575	Identity:	109/575 - (18%)
Similarity:	206/575 - (35%)	Gaps:	111/575 - (19%)

- Green bases have known domain annotations that are detailed below.

Mouse   331 WGQGIDIQRALQ-QVRFEGLTGNVQF-NEKGRRTNYTLHVIEMKHDGIRKIGYWNEDDKFVPAAT 393
            ||..:::|.... .:.:.|....:.: ||..              ||   ..||
  Fly   121 WGVDLEVQSLFPLNLNYVGPNAQITYVNETA--------------DG---YAYW----------- 157

Mouse   394 DAQAGGDNSSVQNRTYIVTTILEDP--------YVMLKKNANQFEG----------------NDR 434
            |..:.|.:........::.|::.|.        ::.......||.|                |::
  Fly   158 DIHSKGRHLKSNLEINLIATLINDTLNIARDIFHLQSIDFRGQFNGLTLRGASVIDKEDIISNEQ 222

Mouse   435 YEGYCVELA--AEIAKHVGYSYRLEIVSDGKYG--ARDPDTKAWNGMVGELVY----------GR 485
            .|.......  |.:|..:.|.|.|..:...::.  ....:::.|.|.:|...:          ..
  Fly   223 IESILSRPTKDAGVAAFIKYHYELLGLLRERFNFTVNFRNSRGWAGRLGNTTFRLGLLGIVMRNE 287

Mouse   486 ADVAVAPLTITLVREEVID-------FSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWM-C 542
            ||:|.:.....:.|....|       |...|:....|.:   ....|.|  :||.|.:..:|: |
  Fly   288 ADIAASGAFNRINRFAEFDTIHQSWKFETAFLYRYTSDL---DTHGKSG--NFLSPFSDRVWLFC 347

Mouse   543 IVFAYIGVSVVLFLVSRFSPYE-----WHSEEFEEGRDQTTSDQSNEFGIFNSLWFSLGAFMQQG 602
            ::  .:|...:::::.....|:     .:|::.|. .:|.:|....:......:..:.||..|||
  Fly   348 LL--TLGAFSIIWVLFEIIDYKILRIRVNSQKLEH-LNQKSSVICIKTTCIERILQTFGACCQQG 409

Mouse   603 CDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLEAG 667
            .|.:|...|.|.:....:.|:|::.:.||:::...|.......|....|..|...:|::.  :.|
  Fly   410 LDPNPVDRSVRFLVMTLFLFSLVMYNYYTSSVVGGLLSSSDQGPSTVDEITASPLKISFE--DIG 472

Mouse   668 STKEFFR----RSKIAVFEKMWTYMKSAEPSVFVRTTEEGMIRVRKSKGKYAYLLE-----STMN 723
            ..|..||    ||...:.||..:..:|..........|:.:..::  .|.:|:..|     ..::
  Fly   473 YYKVLFRESQNRSITRLIEKKLSSSRSLNELPIFSHIEDAVPYLK--AGGFAFHCEVVDAYPVIS 535

Mouse   724 EYIEQRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECG 788
            ||.:..:.||..:|.|.::.:.......|.|........|:....|:|.::::..:....|..|.
  Fly   536 EYFDANEICDLREVSGLMEVEILNWILHKNSQYTEIFKTAMCNAQEKGFVERILRRRQIKKPACQ 600

Mouse   789 SKDSGSKDKTSALSLSNVAGVFYILIGGLGLAMLVALIEFCYKSRSESKRMKGFC 843
            |..:     ...:|||.|...|.|||.|.|.::|:..:|..|......|    ||
  Fly   601 SLYT-----VYPVSLSGVLPGFVILICGFGASLLLLCLEKVYAHFGPRK----FC 646

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.