DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12256 and Prss44

DIOPT Version :9

Sequence 1:	NP_650166.2	Gene:	CG12256 / 14462452	FlyBaseID:	FBgn0038002	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_683742.2	Gene:	Prss44 / 73336	MGIID:	1920586	Length:	372	Species:	Mus musculus

Alignment Length:	243	Identity:	76/243 - (31%)
Similarity:	115/243 - (47%)	Gaps:	23/243 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 RVVGGYDVPEDEYVPYQVSMQFLTRSGKMRHFCGGSLIAPNRVLTAAHCVNGQNASRISVVAGIR 110
            |:|||...|..:: |:|||:|.     ..:|.||||||:...|:||||||.|.  ...:|..|..
Mouse   111 RIVGGRPAPARKW-PWQVSLQV-----HKQHICGGSLISKWWVITAAHCVYGH--LDYAVFMGDA 167

  Fly   111 DLNDSSGFRSQVQSYEMNENYQEL--VTSDIAILKIDPPFELDEKRVSTIDVSGSDMVGADQEVL 173
            ||......|..||...:::::..:  |..|||::.:..|...............|.:|.......
Mouse   168 DLWSKRPVRIPVQDIIVHQDFSMMRTVVHDIALVLLAFPVNYSVNIQPVCIPEKSFLVQPGTLCW 232

  Fly   174 LTGWGSVFHFGTGPFAKYPTVLQKLDYKTLSNSKCKETM--------TQLTDTEICALERFGKGA 230
            :||||.|...|     :...:||:::...:.:.||.:.:        |.:.:..:|.....|..|
Mouse   233 VTGWGKVLEQG-----RSSRILQEIELNIIRHEKCNQILKDIMGNIFTLVQEGGVCGYNEKGGDA 292

  Fly   231 CNGDSGGPLVMKSGESYKQVGVVSYGTAFCASNNPDVYTRVSMFDGWI 278
            |.||||||||.:..:::.|||:||:|........|.|||.||.:..||
Mouse   293 CQGDSGGPLVCEFNKTWVQVGIVSWGLGCGRIGYPGVYTEVSYYRDWI 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12256	NP_650166.2	Tryp_SPc	46..278	CDD:214473	74/241 (31%)
CG12256	NP_650166.2	Tryp_SPc	47..280	CDD:238113	75/242 (31%)
Prss44	NP_683742.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	31..72
		Tryp_SPc	111..340	CDD:214473	74/241 (31%)
		Tryp_SPc	112..340	CDD:238113	73/240 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910