Protein Alignment Cyp2b10 and Cyp303a1

DIOPT Version :10

• Sequence 1: NP_034129.1
• Gene: Cyp2b10 / 13088
• MGIID: 88598
• Length: 491
• Species: Mus musculus
• Sequence 2: NP_652070.1
• Gene: Cyp303a1 / 49165
• FlyBaseID: FBgn0001992
• Length: 503
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 161/525 - (30%)
• Similarity: 252/525 - (48%)
• Gaps: 77/525 - (14%)

Mouse     8 LLALLVGFLLLLARGHPKSRGNFPPGPRPLPLLGNLLQMDRGGLLKSFIQLREKYG------DVF 66
            |||:|.|       |..|.: .|||||...|::|:.||:.         |||.:.|      |||
  Fly    13 LLAILFG-------GVRKPK-RFPPGPAWYPIVGSALQVS---------QLRCRLGMFCKVIDVF 60

Mouse    67 T-----------VHLGPRPVVMLCGTDTIREALVGQAEAFSGR--GTVAVVEPTFKEYGVIFANG 118
            .           :.:|...||:....|.|.|.:..  |...||  |....:.......||:..:|
  Fly    61 ARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDG 123

Mouse   119 ERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELR----KSQG--APLDPTFLFQCITAN 177
            |.|...|||.|..:::||..:..:.:.:..||.||:::|:    ||.|  ..::...|......|
  Fly   124 EMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLN 188

Mouse   178 IICSIVFGERFEYTDRQFLRLLELFYQTFSLIS------------SFSSQMFELFSGFLKYFPGA 230
            .:..::.|.|:|....:..:|||.|::.|..|.            .|.:..|..::||::    :
  Fly   189 TLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVE----S 249

Mouse   231 HRQISKNLQELLDYIGHSVEKHRATL-DPSVPRDFIDIYLLRMEKEKSNQHTEFHHQNLMMSVLS 294
            ||       .|..::...:|.||.|. :...|||.:|.| ||.:.|.:::...|..|:|:...|.
  Fly   250 HR-------SLYTFMSKEIELHRLTYKNYDEPRDLMDSY-LRAQDEGNDEKGMFSDQSLLAICLD 306

Mouse   295 LFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLD-DRTKMPYTDAVIHEIQR 358
            :|.||:||::.:|.:.|:.::..|.:.|:..:||.:|:|..|:|... ||||:||.:|:..|..|
  Fly   307 MFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVR 371

Mouse   359 FSDLIPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANGALKKS 423
            ...|...|:|||...||...||.:||:|.|.......|.:|..|..|:|||||.:| .:|.||..
  Fly   372 MFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL-FDGHLKLP 435

Mouse   424 EAFLPFSTGKRICLGESIARNELFLFFTSILQNFSVAS--HVAPKDIDLTPKESGIGKIPPTYQI 486
            |||.||..|:..|:|:.:.|..||:|.|::||||.:.:  ...|:::   |.|.....:.| |.|
  Fly   436 EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEV---PLEGATAAVKP-YDI 496

Mouse   487 CFLAR 491
            ..:||
  Fly   497 MLVAR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp2b10	NP_034129.1	CYP2B	62..486	CDD:410765	139/464 (30%)
Cyp303a1	NP_652070.1	CYP15A1-like	68..496	CDD:410744	135/446 (30%)