DRSC/TRiP Functional Genomics Resources

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Protein Alignment: CG43446 and SIGMAR1

Sequence 1:NP_001247217.1 Gene:CG43446 FlyBaseID:FBgn0263400 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_005857.1 Gene:SIGMAR1 HGNCID:8157 Length:223 Species:Homo sapiens

Alignment Length:39 Identity:8/40 (20%)
Similarity:17/40 (43%) Gaps:5/40 (13%)


  Fly   219 RKIASFKVMAPDPIYYTILNPGFWP-----KHIIVHEFV 252
            |::....|:..:.:.:..:|.|.|.     .|..:.|:|
Human    66 RRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYV 104

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CG43446NP_001247217.1 PHD_SF 3..58 CDD:304600
SIGMAR1NP_005857.1 Targeting to endoplasmic reticulum-associated lipid droplets. {ECO:0000250|UniProtKB:O55242} 2..8
ERG2_Sigma1R 24..214 CDD:309666 8/40 (20%)
Important for ligand-binding. {ECO:0000250|UniProtKB:Q60492} 99..106 2/7 (29%)
C-terminal hydrophobic region. {ECO:0000269|PubMed:27042935} 177..223
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 FOG0004522
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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