Protein Alignment CG43336 and KLK7

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_005037.1
• Gene: KLK7 / 5650
• HGNCID: 6368
• Length: 253
• Species: Homo sapiens
• Alignment Length: 285
• Identity: 75/285 - (26%)
• Similarity: 115/285 - (40%)
• Gaps: 54/285 - (18%)

  Fly    12 LLPLLGSTQFLDMACGIRAHSPSVPRVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLT 76
            ||||  ....|.:|...........::.:|...:..|.||...|.| ..:..|||.|:..|.|||
Human     6 LLPL--QILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLS-GNQLHCGGVLVNERWVLT 67

  Fly    77 AAHCFLDRTELVARLGE---YDREEYEMCHDSYCTYRIEAMVERGFRHRHYNPMTMAYDIAILRL 138
            ||||.::  |....||.   .||.          ..||:|  .:.|||..|:..|...|:.:::|
Human    68 AAHCKMN--EYTVHLGSDTLGDRR----------AQRIKA--SKSFRHPGYSTQTHVNDLMLVKL 118

  Fly   139 YRKVQYTDNIRPICIVIDPRWRKYIDSLDP----LTGTGWGKTESEGDS--AKLRTVDLARKHPE 197
            ..:.:.:..::.:         :.....:|    .|.:|||.|.|...:  :.|..||:....|:
Human   119 NSQARLSSMVKKV---------RLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174

  Fly   198 VCRRYATLSLTANQFCAG--NERSNLCNGDSGGPV---GALIPYGKSKRFVQVGIASFTNTQCVM 257
            .|.:.....|..:..|||  :.:.|.||||||||:   |.|           .|:.|:....|..
Human   175 DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTL-----------QGLVSWGTFPCGQ 228

  Fly   258 VS---VFTDVMSYVDWILAVHNYHK 279
            .:   |:|.|..:..||......|:
Human   229 PNDPGVYTQVCKFTKWINDTMKKHR 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	66/250 (26%)
KLK7	NP_005037.1	Tryp_SPc	29..245	CDD:214473	66/250 (26%)