Protein Alignment CG43336 and PRSS3

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 74/265 - (27%)
• Similarity: 109/265 - (41%)
• Gaps: 57/265 - (21%)

  Fly    31 HSP----SVP-----RVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLTAAHCFLDRTE 86
            |.|    :||     ::..|......|.|:...|:|  |...||||||:.:.|::||||:  :|.
Human    22 HPPDALIAVPFDDDDKIVGGYTCEENSLPYQVSLNS--GSHFCGGSLISEQWVVSAAHCY--KTR 82

  Fly    87 LVARLGEYDREEYEMCHDSYCTYRIEAMVERGFRHRHYNPMTMAYDIAILRLYRKVQYTDNIRPI 151
            :..||||::.:..|.........:|       .||..||..|:..||.:::|.........:..|
Human    83 IQVRLGEHNIKVLEGNEQFINAAKI-------IRHPKYNRDTLDNDIMLIKLSSPAVINARVSTI 140

  Fly   152 CIVIDPRWRKYIDSLDPLTGT-----GWGKTESEGDS--AKLRTVDLARKHPEVCRRYATLSLTA 209
            .:...|          |..||     |||.|.|.|..  .:|:.:|........|:......:|.
Human   141 SLPTTP----------PAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITN 195

  Fly   210 NQFCAG--NERSNLCNGDSGGPV---GALIPYGKSKRFVQVGIASFTNTQCVMVS---VFTDVMS 266
            :.||.|  ....:.|..||||||   |.|           .|:.|:.: .|...:   |:|.|.:
Human   196 SMFCVGFLEGGKDSCQRDSGGPVVCNGQL-----------QGVVSWGH-GCAWKNRPGVYTKVYN 248

  Fly   267 YVDWI 271
            |||||
Human   249 YVDWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	68/248 (27%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	70/249 (28%)