Protein Alignment CG43336 and TMPRSS11F

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_997290.2
• Gene: TMPRSS11F / 389208
• HGNCID: 29994
• Length: 438
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 80/296 - (27%)
• Similarity: 126/296 - (42%)
• Gaps: 63/296 - (21%)

  Fly     9 TFFLLPLLGS--TQFLDMACGIRAHSPSVP--------RVKNGTVASLTSS-PWMAFLHSTDGRF 62
            :|.|.|:...  ...|:..||||..|.::|        |:..|...::... ||.|.|.......
Human   167 SFRLTPIDSKKMRNLLNSRCGIRMTSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSGH 231

  Fly    63 ICGGSLITNRLVLTAAHCF---LDRTELVARLGEYDREEYEMCHDSYCTYRIEAMVERGFRHRHY 124
            .||.|||:|..:|||||||   .|.|:.:|..|.           :.....::..|.:...|.:|
Human   232 QCGASLISNTWLLTAAHCFWKNKDPTQWIATFGA-----------TITPPAVKRNVRKIILHENY 285

  Fly   125 NPMTMAYDIAILRLYRKVQYTDNIRPIC-----IVIDPRWRKYIDSLDPLTGTGWGKTESEGD-- 182
            :..|...|||:::|...|::::.::.:|     |.:.|:...::        ||:|....:|.
Human   286 HRETNENDIALVQLSTGVEFSNIVQRVCLPDSSIKLPPKTSVFV--------TGFGSIVDDGPIQ 342

  Fly   183 ----SAKLRTVDLARKHPEVCRR---YATLSLTANQFCAG--NERSNLCNGDSGGPVGALIPYGK 238
                .|::.|:.     .:||.|   |..| :|....|||  ..:.:.|.||||||    :.|..
Human   343 NTLRQARVETIS-----TDVCNRKDVYDGL-ITPGMLCAGFMEGKIDACKGDSGGP----LVYDN 397

  Fly   239 SKRFVQVGIASFTNTQCVM---VSVFTDVMSYVDWI 271
            ...:..|||.|: ...|.:   ..|:|.|..|.|||
Human   398 HDIWYIVGIVSW-GQSCALPKKPGVYTRVTKYRDWI 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	68/256 (27%)
TMPRSS11F	NP_997290.2	SEA	59..158	CDD:460188
		Tryp_SPc	206..435	CDD:238113	69/257 (27%)