Protein Alignment CG43336 and KLK1

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 78/272 - (28%)
• Similarity: 108/272 - (39%)
• Gaps: 58/272 - (21%)

  Fly    27 GIRAHSPSVPRVKNGTVASLTSSPWMAFLH--STDGRFICGGSLITNRLVLTAAHCFLDRTELVA 89
            |..|..|...|:..|......|.||.|.|:  ||   |.|||.|:..:.|||||||..|..:|
Human    14 GTGAAPPIQSRIVGGWECEQHSQPWQAALYHFST---FQCGGILVHRQWVLTAAHCISDNYQL-- 73

  Fly    90 RLGEY----DREEYEMCHDSYCTYRIEAMVERGF------RHRHYNPMTMAYDIAILRLYRKVQY 144
            .||.:    |....:..|.|      |:....||      .|........::|:.:|||   .:.
Human    74 WLGRHNLFDDENTAQFVHVS------ESFPHPGFNMSLLENHTRQADEDYSHDLMLLRL---TEP 129

  Fly   145 TDNIRPICIVIDPRWRKYIDSLDPLTG-----TGWGKTESEGDS--AKLRTVDLARKHPEVCRRY 202
            .|.|.....|::      :.:.:|..|     :|||..|.|..|  ..|:.|||.....:.|::.
Human   130 ADTITDAVKVVE------LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKA 188

  Fly   203 ATLSLTANQFCAGNER--SNLCNGDSGGPV---GALIPYGKSKRFVQVGIASFTNTQC---VMVS 259
            ....:|....|.|:..  .:.|.||||||:   |.|           .|:.|:....|   ...|
Human   189 HVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVL-----------QGVTSWGYVPCGTPNKPS 242

  Fly   260 VFTDVMSYVDWI 271
            |...|:|||.||
Human   243 VAVRVLSYVKWI 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	73/260 (28%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	74/261 (28%)