Protein Alignment CG43336 and KLK3

DIOPT Version :10

• Sequence 1: NP_001247122.1
• Gene: CG43336 / 12798414
• FlyBaseID: FBgn0263041
• Length: 279
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 258
• Identity: 76/258 - (29%)
• Similarity: 112/258 - (43%)
• Gaps: 51/258 - (19%)

  Fly    37 RVKNGTVASLTSSPWMAFLHSTDGRFICGGSLITNRLVLTAAHCFLDRTELVARLGEYDREEYEM 101
            |:..|......|.||...:.|. ||.:|||.|:..:.|||||||.  |.:.|..||.:.....|
Human    24 RIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCI--RNKSVILLGRHSLFHPE- 84

  Fly   102 CHDSYCTYRIEAMVERGFRHRHYNPMTM-----------AYDIAILRLYRKVQYTDNIRPICIVI 155
              |:...::    |...|.|..|:...:           ::|:.:|||....:.||.::    |:
Human    85 --DTGQVFQ----VSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVK----VM 139

  Fly   156 DPRWRKYIDSLDPLTGT-----GWGKTESEG--DSAKLRTVDLARKHPEVCRRYATLSLTANQFC 213
            |      :.:.:|..||     |||..|.|.  ...||:.|||.....:||.:.....:|....|
Human   140 D------LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLC 198

  Fly   214 AG--NERSNLCNGDSGGPVGALIPYGKSKRFVQVGIASFTNTQCVM---VSVFTDVMSYVDWI 271
            ||  ....:.|:||||||   |:..|     |..||.|:.:..|.:   .|::|.|:.|..||
Human   199 AGRWTGGKSTCSGDSGGP---LVCNG-----VLQGITSWGSEPCALPERPSLYTKVVHYRKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43336	NP_001247122.1	Tryp_SPc	37..271	CDD:214473	74/256 (29%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	75/257 (29%)